GEO DataSets

(Submitter supplied) Normal adult liver is uniquely capable of renewal and repair after injury. Whether this response represents simple hyperplasia of various liver elements or requires recapitulation of the genetic program of the developing liver is not known. To study these possibilities, we examined transcriptional programs of adult liver after partial hepatectomy and contrasted these with developing embryonic liver. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2577

Platform:

GPL1261

32 Samples

Download data: CEL

Comparison of regenerating liver to developing embryonic liver. Regenerating liver examined at time points up to 72 hours after partial hepatectomy. Developing liver examined up to 16.5 days post conception (dpc). Results provide insight into molecular mechanisms regulating renewal and repair.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 specimen, 16 time sets

Platform:

GPL1261

Series:

GSE6998

32 Samples

Download data: CEL

(Submitter supplied) Liver is uniquely capable to repair itself after injury. Multiple molecular and biochemical processes initiated after partial hepatectomy, lead to proliferation of all cells within the liver. MicroRNAs (miRNAs) are a class of highly abundant non-coding RNA molecules that cause post-transcriptional gene repression and are involved in several biological processes including cell cycle regulation and differentiation. more...

Organism:

Rattus norvegicus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Murid betaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL7723

2 Samples

Download data: TXT

(Submitter supplied) Genome-wide expression analysis revealed that 3653 mRNAs and 465 putative lncRNAs were differentially expressed compared to transcripts isolated from livers of control sham operated mice. Analysis was done using the NCode Mouse Non-coding RNA Microarray (Invitrogen), which contains 25,179 coding featues and 10,802 noncoding features.

Organism:

Mus musculus

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL20668

25 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing; Other; Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL20668 GPL13112

40 Samples

Download data: BW

(Submitter supplied) LncPHx2 RNA-interactome study realed that LncPHx2 is associated with multiple RNAs

Organism:

Mus musculus

Type:

Other

Platform:

GPL13112

3 Samples

Download data: BW

(Submitter supplied) Gene expression analysis showed that LncPHx2 depletion resulted in upregulation of mRNAs encoding proteins known to promote cell proliferation, including MCM components, DNA polymerases, histone proteins, and transcription factors

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13112

12 Samples

Download data: DIFF, FPKM_TRACKING

(Submitter supplied) There are about 600 loci in the mammalian genome that are annotated as RNA polymerase III genes. These comprise tRNA genes, the genes encoding 5S RNA, the smallest ribosomal RNA, and genes encoding catalytic or structural RNAs involved in processes as diverse as RNA processing or transcription elongation. Most RNA polymerase III genes have similar promoter structures, yet they are transcribed with different efficiencies. more...

Organism:

Mus musculus

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL17021

29 Samples

Download data: BW, XLSX

(Submitter supplied) Analysis of gene expression after sham surgery, 70% hepatectomy or 80% hepatectomy in normal mice or mice made obese through feeding of a high-fat diet.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6887

24 Samples

Download data: TXT