GEO DataSets

(Submitter supplied) Small RNA pathways play evolutionarily conserved roles in gene regulation and in defense from pathogenic and parasitic nucleic acids. The character and expression patterns of small RNAs show conservation throughout animal lineages, but specific animal clades also show variations on these recurring themes, including species-specific small RNAs. The monotremes, with only platypus and four species of echidna as extant members, represent the basal branch of the mammalian lineage. more...

Organism:

Tachyglossus aculeatus; Ornithorhynchus anatinus

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL11057 GPL11058

3 Samples

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(Submitter supplied) We collected small RNA sequencing data from brain and heart of an adult Xenopus tropicalis individual to investigate the conservation of site-specific miRNA editing events identified in mammals.

Organism:

Xenopus tropicalis

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL18470

2 Samples

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(Submitter supplied) We explored the potential for small RNA biology in organisms that diverged basal to Bilateria, identifying both miRNAs and piRNAs in Nematsotella and Amphimedon

Organism:

Trichoplax adhaerens; Monosiga brevicollis; Amphimedon queenslandica; Nematostella vectensis

Type:

Non-coding RNA profiling by high throughput sequencing

4 related Platforms

17 Samples

Download data: TXT

(Submitter supplied) All the reports on insect small RNAs come from holometabolous insects. However, small RNAs of hemimetabolous insects have not yet been investigated.Study of hemimetabolous insect small RNAs could provide more insights into evolution and function of small RNAs in hemi- and holometabolous insects. The locust is an important, economically harmful hemimetabolous insect and its phase changes is an interesting phenomenon.Here, we used high-throughput sequencing to characterize and compare the small RNA transcriptomes of gregarious and solitary phases in locusts. more...

Organism:

Locusta migratoria

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL9308

2 Samples

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(Submitter supplied) MicroRNAs (miRNAs) are major post-transcriptional regulators of gene expression, yet their origins and functional evolution in mammals remain little understood due to the lack of appropriate comparative data. Using RNA sequencing, we have generated extensive and comparable miRNA data for five organs in six species that represent all main mammalian lineages and birds (the evolutionary outgroup), with the aim to unravel the evolution of mammalian miRNAs. more...

Organism:

Gallus gallus; Ornithorhynchus anatinus; Didelphis virginiana; Mus musculus; Macaca mulatta; Homo sapiens; Monodelphis domestica

Type:

Non-coding RNA profiling by high throughput sequencing

7 related Platforms

38 Samples

Download data: TXT

(Submitter supplied) Changes in gene expression are thought to underlie many of the phenotypic differences between species. However, large-scale analyses of gene expression evolution were until recently prevented by technological limitations. Here we report the sequencing of polyadenylated RNA from six organs across ten species that represent all major mammalian lineages (placentals, marsupials and monotremes) and birds (the evolutionary outgroup), with the goal of understanding the dynamics of mammalian transcriptome evolution. more...

Organism:

Gorilla gorilla; Homo sapiens; Mus musculus; Monodelphis domestica; Gallus gallus; Ornithorhynchus anatinus; Macaca mulatta; Pan paniscus; Pan troglodytes; Pongo pygmaeus

Type:

Expression profiling by high throughput sequencing

10 related Platforms

131 Samples

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