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Links from GEO DataSets

Items: 4

1.

Gene expression data from S. aureus-exposed macrophages

(Submitter supplied) It is becoming increasingly apparent that Staphylococcus aureus are able to survive engulfment by macrophages, and that the intracellular environment of these cells, which is essential to innate host defenses against invading microorganisms, may in fact provide a refuge for staphylococcal survival and dissemination. Based on this, we postulated that S. aureus might induce cytoprotective mechanisms by changing gene expression profiles inside macrophages similar to obligate intracellular pathogens, such as Mycobacterium tuberculosis. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4931
Platform:
GPL570
30 Samples
Download data: CEL, CHP
Series
Accession:
GSE13670
ID:
200013670
2.
Full record GDS4931

Macrophage response to to Staphylococcus aureus infection in vitro: time course

Analysis of monocyte-derived macrophages that phagocytosed S. aureus in vitro. Monocytes analyzed for up to 48 hours after phagocytosis. Results provide insight into the molecular mechanisms employed by S. aureus to prolong their intracellular survival.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 infection, 3 time sets
Platform:
GPL570
Series:
GSE13670
30 Samples
Download data: CEL, CHP
3.

Time-dependent global gene expression profile of J774A.1 cells treated with ManLAM in the absence or presence of GW9662

(Submitter supplied) Transcriptional profiling of J7774A.1 cells treated with ManLAM ( 5ug/ml) for 6 h in the absence or presence of GW9662
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL13381
8 Samples
Download data: TXT
Series
Accession:
GSE72591
ID:
200072591
4.

Gene expression data from S. aureus-exposed neutrophils

(Submitter supplied) Neutrophil lysis after phagocytosis is a process potentially important in the pathogenesis of community-associated methicillin-resistant S. aureus (CA-MRSA) infection. The mechanism for this process is not currently known. Therefore, to better understand CA-MRSA virulence we used human oligonucleotide microarrays to investigate the mechanism underlying enhanced PMN lysis that occurs after phagocytosis of CA-MRSA. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
113 Samples
Download data: CEL, CHP
Series
Accession:
GSE16837
ID:
200016837
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