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Items: 2

1.

Analysis of altered gene expressions in valproate-treated Disc1-L100P mutant mice

(Submitter supplied) Microarray analysis revealed that changes in genes expressions are brain region-dependent; expression of several genes are affected by point mutation L100P, which was verified by RT-PCR (Lcn2, Cyr61, Slc6a12, Slc40a1, Egr2), a few genes are affected by genotype and valproate (Dusp1 and Purb), suggesting their role in valproate-induced benificial effect on sensorimotor gaiting in Disc1-L100P mutant mice. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
69 Samples
Download data: TIFF, TXT
Series
Accession:
GSE17735
ID:
200017735
2.

Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders

(Submitter supplied) Analysis of gene expression alteration in iPSC-derived cortical neurons with ATF4 overexpression
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21697
6 Samples
Download data: CSV
Series
Accession:
GSE149733
ID:
200149733

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