GEO DataSets

(Submitter supplied) A major development in pigmentation research was the discovery of the involvement of SLC24A5 in natural variation in skin colour. This study used Agilent whole-genome microarrays to examine the impact of SLC24A5 knockdown on the transcriptome of normal human melanocytes derived from lightly and darkly pigmented donors.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4133

30 Samples

Download data: TXT

(Submitter supplied) Ammopiptanthus mongolicus is an ecologically important desert plant. miRNA are endogenous 20-22 nt small RNAs that play important roles in regulating gene expression in plants. To identify to the target genes of miRNA in Ammopiptanthus mongolicus, degradome sequencing was performed and a batch of transcripts were found to be targeted by miRNA. The result is helpful in understanding the roles on miRNA in plant development and environmental stress response.

Organism:

Ammopiptanthus mongolicus

Type:

Expression profiling by high throughput sequencing; Other

Platform:

GPL19805

1 Sample

Download data: TXT

(Submitter supplied) Ammopiptanthus mongolicus is an ecologically important desert plant. To understand the role of miRNA genes in draught and cold stress adaptation, RNA-seq of small RNA in Ammopiptanthus mongolicus was performed.

Organism:

Ammopiptanthus mongolicus

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL19805

5 Samples

Download data: FA

(Submitter supplied) Sunflower is an important source of vegetable oil worlwide. A differential organ-specific sunflower ESTs was previously generated by a subtractive hybridization method, including a considerable number of abiotic stress associated sequences. The objective of this work is to analyze the sunflower gene expression of previously identified candidate genes under a comprehensive microarray analysis of the leaf transcriptoma under cold and salinity stresses, considering the impacts of these abiotic stresses on sunflower yield in many productive areas. more...

Organism:

Helianthus annuus

Type:

Expression profiling by array

Platform:

GPL4366

18 Samples

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(Submitter supplied) We determined the gene expression profiles of murine melan-a melanocytes treated with ASP or alpha-MSH over a 4 days time course using genome-wide oligonucleotide microarrays. As expected, the gene expression patterns emphasized the opposing effects of the 2 ligands, and there were significant reductions in expression of numerous melanogenic proteins elicited by ASP, which correlates with its inhibition of pigmentation. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4200

59 Samples

Download data: GPR

(Submitter supplied) Total RNA was extracted from three partially overlapping dorsal skin layers derived from P2.5 normal (E+/E+) and recessive yellow (e/e) mice, as well as from an immortalized mouse melanocyte cell line (melan-a). Replicate samples (cy5) were labelled and co-hybridized with a reference RNA sample (cy3) to a 26K mouse cDNA microarray. A reference experiment design type is where all samples are compared to a common reference. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3798

24 Samples

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(Submitter supplied) Adult human fibroblasts derived from the dermis of 4 mm punch biopsies taken from the lower backs of 15 healthy subjects of 3 different phototypes (types I, III and VI). This study was approved by the Human Research Ethics Committee of Hamburg. Subjects with type I skin were #4, 12, 15, 19 and 26; subjects with type III skin were # 6, 9, 13, 14 and 23, and subjects with type VI skin were # 7, 8, 16, 17 and 28. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL3779

15 Samples

Download data: GPR

(Submitter supplied) To understand molecular mechanism of stripe patterning in the embryonic skin of Japanese quail, we compared gene expression profile between black stripe and yelllow stripe by using RNA seq method. Most of differential expression genes were known pigmentation-related genes, but some are unknown role in pigment pattern formation.

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25495

4 Samples

Download data: XLSX

(Submitter supplied) O. rhodostigmatus are non-obligative cave dwellers, whose tadpoles keep albinistic phenotype in caves but rapidly darken in light within 24 hours. Their coloration system is an excellent model for exploring the processes and mechanisms of light-induced pigmentation and revealing the genetic adaptation for non-obligative cave dwelling due to complicated life history. Using comparative transcriptomics, we found that melanocyte MCC (including melanogenesis and melanocytes proliferation) was responsible for the rapid skin darkening in was activated in O. more...

Organism:

Oreolalax rhodostigmatus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24240

13 Samples

Download data: FASTA, XLSX