Similar studies for GEO DataSets (Select 200021622) - GEO DataSets

Select item 2000216221.

Response of Candida albicans towards a novel antifungal benzimidazole derivative

(Submitter supplied) Fungal infections are a serious health problem in the clinic especially in the immunocompromised patient. Disease ranges from widespread superficial vulvovaginal infections to life-threatening systemic candidiasis. Especially for systemic mycoses only a limited arsenal of antimycotica are available, including azoles, polyenes, echinocandines and amphothericin B. Due to emerging resistance to standard therapy and significant side effects for some antimycotica there is a medical need for new antifungals in the clinic and general practice. more...

Organism:: Candida albicans SC5314; Candida albicans

Type:: Expression profiling by array

Platform:: GPL10374
6 Samples

Download data: GPR

Series

Accession:: GSE21622

ID:: 200021622

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000649762.

An antifungal benzimidazol reveals novel sterols after inhibition of Erg11.

(Submitter supplied) Fungal infections are a serious health problem in clinics especially in the immune-compromised patient. Disease ranges from widespread superficial infections like vulvovaginal infections to life-threatening systemic candidiasis. Especially for systemic mycoses only a limited arsenal of antifungals is available. The most commonly used classes of antifungal compounds used include azoles, polyenes and echinocandines. more...

Organism:: Candida albicans SC5314; Candida albicans

Type:: Expression profiling by array

Platform:: GPL10374
18 Samples

Download data: GPR

Series

Accession:: GSE64976

ID:: 200064976

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000321193.

Host and pathogen interaction: time course

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Candida albicans; Danio rerio

Type:: Expression profiling by array

Platforms:: GPL6457 GPL14575
54 Samples

Download data: TXT

Series

Accession:: GSE32119

ID:: 200032119

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000321184.

Host and pathogen interaction: time course [zebrafish]

(Submitter supplied) The interaction between fungal pathogen and host during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histological analysis of surviving fish were sampled at different post-infection time points. The dynamic variations of significant genes expression profiles in C. more...