GEO DataSets

(Submitter supplied) This purpose of this experiment was to investigate the transcriptional differences between mice infected with SARS MA15 or SARS nsp16 mutant viruses.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL7202

40 Samples

Download data: TXT

(Submitter supplied) Severe acute respiratory syndrome coronavirus (SARS-CoV) causes a respiratory disease leading to death in 10% of the infected people. A mouse adapted SARS-CoV lacking the envelope (E) protein (rSARS-CoV-MA15-ΔE) is attenuated in vivo. To identify E protein domains and host responses that contribute to rSARS-CoV-MA15-ΔE attenuation, several mutants (rSARS-CoV-MA15-E*) containing point mutations or deletions in the amino-terminal or the carboxy-terminal regions of E protein, respectively, were generated. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL13912

15 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus; Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

5 related Platforms

2549 Samples

Download data: TXT

(Submitter supplied) The purpose of this experiment was to obtain samples for transcriptome analysis using wild type infectious clone of Middle Eastern Respiratory Syndrome (icMERS) coronavirus and icMERS mutant viruses: icMERS-RFP, icMERS-dNSP16, icMERS-d4B, and icMERS-d3-5. For protocol details, please search for the protocol ID at https://systemsvirology.org.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL13497 GPL19730

95 Samples

Download data: TXT

(Submitter supplied) To better understand the biological pathways by which UV inactivated SARS-CoV-induced pulmonary eosinophilia occurs, we examined global transcriptional changes in macrophages from the lungs of mouse.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL10787

24 Samples

Download data: TXT

(Submitter supplied) To better understand the biological pathways by which UV inactivated SARS-CoV-induced pulmonary eosinophilia occurs, we examined global transcriptional changes in mouse lungs.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL10787

24 Samples

Download data: TXT