GEO DataSets

(Submitter supplied) RAW264.7 macrophages infected with MNV-1 and mock infected gene expression measured by microarray. To be published in Waugh, E. Chen, A. Baird, M. Fleming, S. Brown, C.M. and V K. Ward (2014) Characterization of the chemokine response of RAW264.7 cells to infection by murine norovirus. Virus Genes

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5356

Platform:

GPL1261

4 Samples

Download data: CEL

Analysis of RAW264.7 macrophage cells infected with murine norovirus (MNV-1). MNV-1 is used a model for human norovirus infection. Results provide insight into the molecular nature of the immune response to norovirus infection.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 infection sets

Platform:

GPL1261

Series:

GSE50093

4 Samples

Download data: CEL

(Submitter supplied) Changes in gene expression on MNV infection of RAW264.7 cells

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

4 Samples

Download data: CEL

(Submitter supplied) Noroviruses have been widely recognized for their importance as causative agents of non-bacterial gastroenteritis. Mouse norovirus is the only representative of the norovirus genus, family Caliciviridae, able to grow in cell culture. The aim of this study is to describe the differences in the expression profiles of MNV-1 and mock-infected macrophages (RAW 264.7 cells), in order to better understand the response of the host cell to norovirus infection. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3549

Platform:

GPL1261

6 Samples

Download data: CEL, CHP

Analysis of macrophage RAW264.7 cells infected with murine norovirus type 1. Noroviruses cause non-bacterial gastroenteritis in humans. Results provide insight into the molecular pathogenesis of norovirus infections.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 infection sets

Platform:

GPL1261

Series:

GSE12518

6 Samples

Download data: CEL, CHP

(Submitter supplied) This study aimed to generate a comprehensive analysis of changes in the transcriptome following MNV infection. Furthermore, we aimed to perform a differential gene expression analysis between MNV infection and loxoribine (tlr7 agonist) treatment to delineate features of the host modified directly by the MNV as opposed to indirect changes induced through IFN signalling.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19057

12 Samples

Download data: TXT

(Submitter supplied) The transcriptome has an abundance of information about the function of individual cells, tissues and an organism in general. Characterising the transcriptome of virus infected cells can illuminate features of the viral-host relationship that are important for pathogenesis. This study broadly aimed to quantify the host gene expression changes that occur following MNV infection. Furthermore, we aimed to identify alterations in specific biological pathways by identifying alterations in transcript abundance that increase or decrease in intensity with MNV infection over time.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19057

6 Samples

Download data: TXT