Similar studies for GEO DataSets (Select 200059357) - GEO DataSets

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Items: 4

Select item 2000593571.

Gene expression profiles of dasatinib-resistant and dasatinib-sensitive pancreatic cancer cell lines

(Submitter supplied) Gene profiles from three dasatinib-resistant and three dasatinib-sensitive pancreatic cancer cell lines were compared by microarray analysis.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5627
Platform:: GPL10558
18 Samples

Download data: TXT

Series

Accession:: GSE59357

ID:: 200059357

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 56272.

Dasatinib-resistant and dasatinib-sensitive pancreatic cancer cell lines

Analysis of dasatinib-resistant and dasatinib-sensitive PC cell lines. Dasatinib, a small-molecule kinase inhibitor, is FDA-approved for PC, but certain PC cells can have intrinsic or acquired resistance to dasatinib. Results provide insight into molecular basis of dasatinib-resistance in PC cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 6 cell line, 2 cell type sets

Platform:: GPL10558
Series:: GSE59357
18 Samples

Download data

DataSet

Accession:: GDS5627

ID:: 5627

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000367033.

CDK-4 inhibitor P276-00 sensitizes Pancreatic Cancer cells to Gemcitabine induced Apoptosis

(Submitter supplied) Despite advances in molecular pathogenesis, pancreatic cancer remains a major unsolved health problem. It is a rapidly invasive, metastatic tumor that is resistant to standard therapies. The phosphatidylinositol-3-kinase (PI3K)/Akt and mammalian target of rapamycin (mTOR) signaling pathways are frequently dysregulated in pancreatic cancer. Gemcitabine (Gem) is the mainstay treatment for metastatic pancreatic cancer. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL15371
14 Samples

Download data: TXT

Series

Accession:: GSE36703

ID:: 200036703

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000358184.

A panel of hepatocellular carcinoma cell lines recapitulates the molecular subtypes of the human disease: A model for targeted drug development

(Submitter supplied) RNA expression patterns of liver cell lines were compared to those of liver tumors to determine the suitability of cell lines as a model for drug development studies. The cell lines appear to recapitulate liver tumors.