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Links from GEO DataSets

Items: 20

1.

Regulation of Activation-Associated MicroRNA Accumulation Rates during Monocyte-to-Macrophage Differentiation

(Submitter supplied) We profiled miRNA expression using TaqMan TLDA assays to identify miRNAs with expression levels that were affected by differences in culturing conditions during monocyte-to-macrophage differentiation.
Organism:
Homo sapiens
Type:
Expression profiling by RT-PCR
Platform:
GPL14851
9 Samples
Download data: TXT
Series
Accession:
GSE60110
ID:
200060110
2.

Regulation of Activation-Associated mRNA and MicroRNA Accumulation Rates during Monocyte-to-Macrophage Differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by RT-PCR
Platforms:
GPL19055 GPL14851
57 Samples
Download data
Series
Accession:
GSE60550
ID:
200060550
3.

Regulation of Activation-Associated Transcripts Accumulation Rates during Monocyte-to-Macrophage Differentiation

(Submitter supplied) We profiled macrophage activation-associated transcripts using TaqMan assays in a Fluidigm 48.48 Gene Expression Array to identify transcripts with expression levels that were affected by differences in culturing conditions during monocyte-to-macrophage differentiation.
Organism:
Homo sapiens
Type:
Expression profiling by RT-PCR
Platform:
GPL19055
48 Samples
Download data: TXT, XLS
Series
Accession:
GSE60549
ID:
200060549
4.

MiRNA expression profile in the aortas of Apoe-/- mice with an specific knock-out of Dicer in endothelial cells compared to control mice after 4 weeks of a high-fat diet

(Submitter supplied) Increased monocyte adhesion to dysfunctional endothelial cells (ECs) orchestrated by chemokines plays an important role in arterial inflammation during atherosclerosis. Endothelial microRNAs (miRNAs) processed by the RNase Dicer1 determine the phenotype of ECs by posttranscriptional regulation of gene expression. However, the impact of endothelial miRNAs on endothelial inflammation and atherosclerosis is currently unclear. more...
Organism:
Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL18082
6 Samples
Download data: TXT
Series
Accession:
GSE53435
ID:
200053435
5.

MiRNA profiling in aortas of Apoe-/- mice with an specific knock-out of Dicer in endothelial cells compared to control mice after 12 weeks of a high-fat diet

(Submitter supplied) Increased monocyte adhesion to dysfunctional endothelial cells (ECs) orchestrated by chemokines plays an important role in arterial inflammation during atherosclerosis. Endothelial microRNAs (miRNAs) processed by the RNase Dicer1 determine the phenotype of ECs by posttranscriptional regulation of gene expression. However, the impact of endothelial miRNAs on endothelial inflammation and atherosclerosis is currently unclear. more...
Organism:
Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL18082
6 Samples
Download data: TXT
Series
Accession:
GSE53433
ID:
200053433
6.

NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation

(Submitter supplied) In this study, analysis of miRNA expression changes in osteoclast differentiation from human primary monocytes revealed the rapid upregulation of two miRNA clusters, miR-212/132 and miR-99b/let-7e/125a. We demonstrate that they negatively target monocyte-specific and immunomodulatory genes like TNFAIP3, IGF1R and IL15. Depletion of these miRNAs inhibits osteoclast differentiation and upregulates their targets. more...
Organism:
Homo sapiens
Type:
Expression profiling by RT-PCR
Platform:
GPL18510
9 Samples
Download data: XLS
Series
Accession:
GSE63773
ID:
200063773
7.

The IL4-STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; synthetic construct; Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL6246 GPL8786
21 Samples
Download data: CEL, CHP
Series
Accession:
GSE71644
ID:
200071644
8.

Negative control and mir-342-3p mimics-transfected RAW264.7 mouse macrophages.

(Submitter supplied) RAW264.7 mouse macrophages were transfected with negative control and miR-342-3p mimics and subjected to microarray analysis 18 hours after the transfection. We used microarray to obtain global mRNA expression data of negative control and miR-342-3p mimics-transfected RAW264.7 cells.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE71642
ID:
200071642
9.

Human periheral blood-derived monocytes and unstimulated as well as IL-4-stimulated differentiating macrophages

(Submitter supplied) CD14+ monocytes were separated from human peripheral blood and exposed to IL-4 for 12 or 72 hours then subjected to microarray analysis We used Affymetrix miRNA1.0 microarray to obtain global miRNA expression data of human monocytes, unstimulated and IL-4-stimulated differentiating macrophages.
Organism:
Homo sapiens; synthetic construct
Type:
Non-coding RNA profiling by array
Platform:
GPL8786
15 Samples
Download data: CEL, CSV
Series
Accession:
GSE71641
ID:
200071641
10.

MiRNA expression profile in murine

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL15053
28 Samples
Download data
Series
Accession:
GSE34648
ID:
200034648
11.

MiRNA expression profile in murine advanced atherosclerotic plaque compared with early atherosclerotic plaque

(Submitter supplied) Aberrantly expressed miRNAs contribute to developmental abnormalities and diseases such as cancer, diabetes, and cardiovascular disorders, by hybridizing to specific mRNA targets and repressing their translation into proteins. Although miRNA expression signature is characterized in the process of neointimal thickening during proliferative vascular diseases such as atherosclerosis, so far global miRNA expression profiling in the different stages of atherosclerosis is completely unknown. more...
Organism:
Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL15053
7 Samples
Download data: XLSX
Series
Accession:
GSE34647
ID:
200034647
12.

MiRNA expression profile in murine un-diseased arterial tissue on 3 month high fat diet vs 10 month high fat diet

(Submitter supplied) Aberrantly expressed miRNAs contribute to developmental abnormalities and diseases such as cancer, diabetes, and cardiovascular disorders, by hybridizing to specific mRNA targets and repressing their translation into proteins. Although miRNA expression signature is characterized in the process of neointimal thickening during proliferative vascular diseases such as atherosclerosis, so far global miRNA expression profiling in the different stages of atherosclerosis is completely unknown. more...
Organism:
Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL15053
7 Samples
Download data: XLSX
Series
Accession:
GSE34646
ID:
200034646
13.

MiRNA expression profile in murine early atherosclerotic plaque compared with un-diseased arterial tissue

(Submitter supplied) Aberrantly expressed miRNAs contribute to developmental abnormalities and diseases such as cancer, diabetes, and cardiovascular disorders, by hybridizing to specific mRNA targets and repressing their translation into proteins. Although miRNA expression signature is characterized in the process of neointimal thickening during proliferative vascular diseases such as atherosclerosis, so far global miRNA expression profiling in the different stages of atherosclerosis is completely unknown. more...
Organism:
Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL15053
8 Samples
Download data: XLSX
Series
Accession:
GSE34645
ID:
200034645
14.

MiRNA expression profile in murine advanced atherosclerotic plaque compared with un-diseased arterial wall

(Submitter supplied) Aberrantly expressed miRNAs contribute to developmental abnormalities and diseases such as cancer, diabetes, and cardiovascular disorders, by hybridizing to specific mRNA targets and repressing their translation into proteins. Although miRNA expression signature is characterized in the process of neointimal thickening during proliferative vascular diseases such as atherosclerosis, so far global miRNA expression profiling in the different stages of atherosclerosis is completely unknown. more...
Organism:
Mus musculus
Type:
Expression profiling by RT-PCR
Platform:
GPL15053
6 Samples
Download data: XLSX
Series
Accession:
GSE34644
ID:
200034644
15.

miRCURY LNATM microRNA Array (7th Gen) profiling of monocyte-derived macrophages and monocyte-derived dendritic cells.

(Submitter supplied) To examine the miRNA changes that occur during macrophage and dendritic cell differentiation we used the miRCURY LNATM microRNA Array (7th Gen) to profile monocyte-derived macrophages and monocyte-derived dendritic cells. Of the 2046 probes present on the assay, we detected expression of ~400 (20%) miRNAs across all samples.
Organism:
JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Cytomegalovirus; Human polyomavirus 1; Human alphaherpesvirus 2; Lymphocryptovirus; Homo sapiens; Human alphaherpesvirus 1; Rhadinovirus; Macaca mulatta polyomavirus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL19128
90 Samples
Download data: TXT, XLSX
Series
Accession:
GSE60839
ID:
200060839
16.

Re-evaluation of the roles of DROSHA, Exportin 5, and DICER in microRNA biogenesis

(Submitter supplied) Biogenesis of canonical microRNAs (miRNAs) involves multiple steps: nuclear processing of primary miRNA (pri-miRNA) by DROSHA, nuclear export of precursor miRNA (pre-miRNA) by Exportin 5 (XPO5), and cytoplasmic processing of pre-miRNA by DICER. To gain a deeper understanding of the contribution of each of these maturation steps, we deleted DROSHA, XPO5, and DICER in the same human cell line, and analyzed their effects on miRNA biogenesis. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL15520
9 Samples
Download data: TXT
Series
Accession:
GSE77989
ID:
200077989
17.

miRNA in mouse macrophages

(Submitter supplied) By employing miRCURY LNA™ microRNA Array, we have identified a subset of 21 top miRNAs that are differentially expressed between GM-BMM and M-BMM cells
Organism:
Mus musculus; Human gammaherpesvirus 4; Human gammaherpesvirus 8; Human polyomavirus 1; Homo sapiens; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Merkel cell polyomavirus; Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Murid gammaherpesvirus 4; Human alphaherpesvirus 1; Mus musculus cytomegalovirus 2; Macaca mulatta polyomavirus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL11434
4 Samples
Download data: TXT
Series
Accession:
GSE46085
ID:
200046085
18.

Regulation of miRNAs in macrophages in response to Candida albacans

(Submitter supplied) In this study we have analysed the regulation of miRNA in bone marrow derived macrophages in response to the fungal pathogen heat killed Candida albicans and bacterial cell wall component, LPS. The aim of the study was to identify and validate miRNAs involved in the innate immune system in response to fungal and bacterial stimuli and investigate potential mechanisms for their transcription.
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL10458
5 Samples
Download data: XLS
Series
Accession:
GSE21970
ID:
200021970
19.

Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; synthetic construct
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL14613 GPL11078
18 Samples
Download data: CEL
Series
Accession:
GSE49331
ID:
200049331
20.

Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia (miRNA)

(Submitter supplied) The aim of this study was to determine the role that miRNAs have on influencing murine microgial phenotypes under M1(LPS) and M2a (IL-4) stimulating conditions. This Series includes expression data obtained from miRNA gene expression microarrays; mRNA expression profiles obtained from the same RNA samples were deposited as a separate Series.
Organism:
synthetic construct; Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL14613
9 Samples
Download data: CEL
Series
Accession:
GSE49330
ID:
200049330
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