GEO DataSets

(Submitter supplied) Zebrafish is a model system being used in a variety of basic research and biomedical studies. Understanding the neurotranscriptomic architecture will greatly facilitate and enhance interpretation of research projects. Studies have reported that there are strain and sex-specific behavioral variation particulary in response to stress and anxiety-inducing scenarios. Capitalizing on previously documented behavioral variation by strains and sex of zebrafish, this study seeks to understand the neurotranscriptomic mechanisms potentially underlying this variation. more...

Organism:

Danio rerio

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15583

16 Samples

Download data: TXT

(Submitter supplied) A microarray study of sex- and gonad-biased gene expression was conducted to determine whether zebrafish demonstrate male-specific patterns consistent with those observed in other animals. We identified a large number of genes (5899) demonstrating statistical differences in transcript abundance between male and female Danio rerio. All sex-biases in gene expression were due to differences between testis and ovary, although differences between male and female body likely went undetected due to constraints imposed by study design and statistical criteria. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL1319

12 Samples

Download data: CEL

(Submitter supplied) Sexual differentiation in vertebrates is initiated during embryogenesis and leads to the development of individuals into phenotypic males or females. The molecular pathways showing sexual dimorphic patterns have been principally investigated in the gonads. In other organs, much less is known about the gender-associated pattern of gene expression. The brain plays a coordinating role on sexual function in both genders including regulation of reproductive development and maturation through the synthesis of neuropeptide hormones and the regulation of sexual behavior in both males and females. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL4375

11 Samples

Download data: TXT

(Submitter supplied) Domesticated animal populations often show profound reductions in predator avoidance and fear-related behavior compared to wild populations. These reductions are remarkably consistent and have been observed in a diverse array of taxa including fish, birds, and mammals. Experiments conducted in common environments indicate that these behavioral differences have a genetic basis. In this study, we quantified differences in fear-related behavior between wild and domesticated zebrafish strains and used microarray analysis to identify genes that may be associated with this variation. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL1319

16 Samples

Download data: CEL

(Submitter supplied) RNA-Seq was performed on mESCs generated from F1 hybrids from reciprocal crosses of C57BL/6J and CAST/EiJ, denoted B and C hereafter; cell lines are designated as BC or CB, with the maternal line symbolized first

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

14 Samples

Download data: TXT

(Submitter supplied) Individual stress coping style has profound effects on how animals respond to environmental change, and individuals within a population strikingly differ in how gene expression shifts in response to challenge. This study used a wild type Zebrafish (Danio rerio) population to: 1) identify and screen for individual coping style using a screening protocol for risk taking in groups and 2) do global transcriptomics of brains from proactive, reactive or randomly chosen individuals (n=10/group) under control conditions. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL6457

30 Samples

Download data: TXT

(Submitter supplied) Sexual reproduction is a complex process involving multiple pathways. In this study, we aimed at investigating gene expression profiles underlying gender specificity in the zebrafish. To do so, we analyzed the transcriptome of the gonads of breeding fish and queried the gene expression profiles for significant differences between the genders and also between stages of gonad development. Major differences in gene expression profiles between genders were encountered at the level of the gonads. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL4375

11 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of zebrafish (Danio rerio) livers comparing control untreated fish with fish treated with estrogen [17β-estradiol (E2)] for different time points (4, 12, 24, 48 hours).

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL15450

12 Samples

Download data: TXT

(Submitter supplied) Sexual dimorphic methylation patterns in IL1b and Casp9 in the zebrafish gonads

Organism:

Danio rerio

Type:

Methylation profiling by high throughput sequencing

Platform:

GPL18413

19 Samples

Download data: CSV, TXT

(Submitter supplied) Methylmercury (MeHg) is a potent neurotoxin and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. We investigated the gene expression profile in adult female zebrafish whole brain induced by acute (96 hr) MeHg exposure. Fish were exposed by injection to 0 or 0.5 µg MeHg/g. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2878

9 Samples

Download data: TXT

(Submitter supplied) The purpose of this experiment was to determine the expression traits in animals of inbred strain C57BL/6J, treated with gonadal hormones. (N=40, 20 males and 20 females).

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

40 Samples

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(Submitter supplied) The purpose of this experiment was to determine the expression traits in Liver tissue from the Four Core Genotype treated group. Keywords: Sry transgene Four Core Genotype Mouse liver Tissue

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

20 Samples

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(Submitter supplied) To determine the expression of cytochrome P450 genes during normal development

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL11077

24 Samples

Download data: TXT

(Submitter supplied) Public information is widely available at low cost to animals living in social groups. For instance, bystanders may eavesdrop on signaling interactions between conspecifics and use it to adapt their subsequent behavior towards the observed individuals. This social eavesdropping ability is expected to require specialized mechanisms such as social attention, which selects social information available for learning. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL20312

12 Samples

Download data: CEL

(Submitter supplied) We describe for the first time transcripts induced after infection of zebrafish with VHSV. Two days after infection, differentially expressed transcript levels from selected immune-related zebrafish genes were studied using qRT-PCR in both fins and internal organs (pooled spleen, head kidney and liver).

Organism:

Danio rerio

Type:

Expression profiling by RT-PCR

Platform:

GPL9804

18 Samples

Download data: TXT

(Submitter supplied) We describe for the first time transcripts induced after infection of zebrafish with viral haemorrhagic septicemia rhabdovirus (VHSV). Two days after infection, differentially expressed transcript levels from selected immune-related zebrafish genes were studied in both fins and internal organs (pooled spleen, head kidney and liver).

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7301

16 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of cadmium (II) chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in cadmium-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

22 Samples

Download data: TXT

(Submitter supplied) We performed microarray-based expression profiling on liver of female zebrafish exposed to 30 µg/L of cadmium (II) chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in cadmium-induced adaptive responses under in vivo environment.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL2715

22 Samples

Download data: TXT

(Submitter supplied) Gene expression analyses have been performed on brain tissue of sexually mature and immature males using microarrays. 60 eels were transferred to two independent temperature controlled recirculation water units connected to two 500 L cylindro-conical tanks (30 fish per tank) where the fish were acclimated to seawater (35 PSU salinity) over a 2 week period.Eel males in one of the seawater units were injected intramuscularly every week over a 140 day period with 2000 IU hCG/kg (human chorionic gonadotropin, Sigma–Aldrich Chemical) dissolved in 0.9% saline to induce sexual maturation. more...

Organism:

Anguilla anguilla

Type:

Expression profiling by array

Platform:

GPL15124

8 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Danio rerio

Type:

Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:

GPL10816 GPL14875

10 Samples

Download data: BW, TXT