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IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation
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Expression data on human MO-to-DC and MO-to-MAC differentiation
Methylation data and effect of JAK3 inhibition on human MO-to-DC and MO-to-MAC differentiation
Comparison of the DNA methylation profiles of CD14+ monocytes from human peripheral blood with DCs and MACs obtained by exposure with GM-CSF/IL-4 and GM-CSF, respectively, and with mature DCs and MACs after LPS exposure
Extensive overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte-derived differentiating macrophages
PubMed Similar studies SRA Run Selector
The IL4-STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p
Negative control and mir-342-3p mimics-transfected RAW264.7 mouse macrophages.
Human periheral blood-derived monocytes and unstimulated as well as IL-4-stimulated differentiating macrophages
miRCURY LNATM microRNA Array (7th Gen) profiling of monocyte-derived macrophages and monocyte-derived dendritic cells.
PubMed Full text in PMC Similar studies
Stat6 mediated regulation of transcription to initiate Th2 program in human T cells
Genome-wide analysis of early transcriptional events induced by cytokine IL-4 in human cord blood CD4+ T cells
Genome-wide analysis of STAT6 target genes in IL-4 treated human cord blood CD4+ cells
Genome-wide detection of STAT6 binding sites in IL-4 treated naive human CD4+ T cells
PubMed Full text in PMC Similar studies SRA Run Selector
Comparative DNA methylation profiling of human monocyte-derived macrophages and dendritic cells
Expression analysis of dendritic cells, macrophages and monocytes
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES
PubMed Similar studies
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq]
PubMed Similar studies Analyze with GEO2RSRA Run Selector
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [ATAC-seq]
PubMed Similar studies Analyze with GEO2R
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY PROGRAM ASSOCIATED WITH THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [EXPRESSION DATA SET]
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