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Links from GEO DataSets

Items: 3

1.

Comparison of expression data between control and Bdh2 morphant zebrafish embryos, as well as Bdh2 morphant zebrafish embryos expressing ectopic Bdh2

(Submitter supplied) Bdh2 morphants displayed mitochondrial dysfunction and degradation by autophagy, which could be restored by ectopic Bdh2 overexpression.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL1319
5 Samples
Download data: CEL, CHP
Series
Accession:
GSE76509
ID:
200076509
2.

Comparison of expression data between control, Atg7, Bdh2, Atg7 and Bdh2 dual morphant zebrafish embryos

(Submitter supplied) Bdh2 morphants displayed mitochondrial dysfunction and degradation by autophagy, as well as hypohemoglobinization. Suppression of Atg7 expression in Bdh2 morphants diminished mitochondrial clearance and partly corrected their hemoglobinization defect.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL1319
10 Samples
Download data: CEL, CHP
Series
Accession:
GSE76508
ID:
200076508
3.

Distinct roles of Bdh2 in regulating embryonic stem cell fate

(Submitter supplied) To further gain insights into the role of Bdh2 in cell fate decisions of mouse ESCs, we generated Bdh2 homozygous knockout mouse advanced pluripotent embryonic stem cell (ASC) and embryonic stem cell (ESC) lines by CRISPR/Cas9 genome editing technology. Bdh2 deficiency in ASCs/ESCs exhibited no effect on expression of core pluripotent transcription factors and alkaline phosphatase activity, suggesting dispensability of Bdh2 for self-renewal and pluripotency of embryonic stem cells. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
6 Samples
Download data: TXT
Series
Accession:
GSE158256
ID:
200158256
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