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Items: 4

1.

mRNA expression profile in Al2O3 nanoparticle treated A549 cells

(Submitter supplied) We evaluated the profile of mRNA expression in control and 100 μg/ml Al2O3 nanoparticle treated A549 cells using the Arraystar Human LncRNA Array v3.0 array,7th generation. Our findings implicates that dysregulation of cell death and cell cycle invovled mRNAs may play important role in cytotoxicity of Al2O3 nanoparticles.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL16956
6 Samples
Download data: TXT
Series
Accession:
GSE77355
ID:
200077355
2.

Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in a murine model

(Submitter supplied) TGFβ inhibition attenuates chronic cigarette smoke induced lung injury and rescues lung architecture.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL8389
20 Samples
Download data: TXT
Series
Accession:
GSE33561
ID:
200033561
3.

Irp2 mediates cigarette smoke-induced bronchitis and emphysema via regulation of cytochrome c oxidase and mitochondrial iron loading

(Submitter supplied) Chronic obstructive pulmonary disease (COPD), the fourth leading cause of death globally, is influenced by both cigarette smoking and genetic determinants. We have previously identified iron-responsive element binding protein 2 (IRP2) as a candidate COPD susceptibility gene based on genetic association studies, with IRP2 increased in the lungs of COPD patients. Here we demonstrate that mice deficient in IRP2 are protected from cigarette smoke (CS)-induced COPD. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
6 Samples
Download data: TXT
Series
Accession:
GSE57073
ID:
200057073
4.

Irp2 mediates cigarette smoke-induced bronchitis and emphysema via regulation of cytochrome c oxidase and mitochondrial iron loading.

(Submitter supplied) Chronic obstructive pulmonary disease (COPD), the fourth leading cause of death globally, is influenced by both cigarette smoking and genetic determinants. We have previously identified iron-responsive element binding protein 2 (IRP2) as a candidate COPD susceptibility gene based on genetic association studies, with IRP2 increased in the lungs of COPD patients. Here we demonstrate that mice deficient in IRP2 are protected from cigarette smoke (CS)-induced COPD. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL17777
11 Samples
Download data: CEL
Series
Accession:
GSE57048
ID:
200057048
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