GEO DataSets

(Submitter supplied) This is part of a cross-species approach to characterize transcriptional response of the insect prothoracic gland (PG) to the prothoracicotropic hormone (PTTH). Genome-wide response of the PG to PTTH was analyzed in vitro in Bombyx and in vivo in Drosophila, and the results were compared to identify common components in the PTTH signaling pathway.

Organism:

Bombyx mori

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16216

4 Samples

Download data: XLSX

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Bombyx mori; Drosophila melanogaster

Type:

Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:

GPL15486 GPL16216

46 Samples

Download data: PAIR, XYS

(Submitter supplied) Samples 1-24: Tissue-specific gene expression microarrays (Nimblegen) using dissected ring glands isolated from FOUR different time points of control (w1118, otherwise wild type) third instar larvae. Time points are 4, 8, 24 and 36 hours after the molt from second to third instar larvae. Samples 25-42: Tissue-specific gene expression microarrays (Nimblegen) using dissected ring glands isolated from TWO different time points of third instar larvae. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL15486

42 Samples

Download data: PAIR, XYS

(Submitter supplied) Samples 1-8: Tissue-specific RNA sequencing (Illumina) using dissected ring glands isolated from TWO different time points of control (phm>w1118) third instar larvae. Time points are: light phase zt0-4 (which corresponde to 2-4 hours from second to third instar larvae molt); and dark phase zt18-22 (which corresponde to 16-20 hours from second to third instar larvae molt) Samples 9-32: Tissue-specific gene expression (RNA seq Illumina) using dissected ring glands isolated from TWO different time points of third instar larvae. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13304

16 Samples

Download data: XLSX

(Submitter supplied) In Drosophila melanogaster larvae the ring gland is a control center that orchestrates major developmental transitions. It is a composite organ, consisting of the prothoracic gland, the corpus allatum and the corpora cardiaca, each of which synthesizes and secretes a different hormone. Until now, the ring gland’s broader developmental roles beyond endocrine secretion have not been explored. RNA sequencing and analysis of a new transcriptome resource from D. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing; Third-party reanalysis

Platform:

GPL13304

6 Samples

Download data: DIFF

(Submitter supplied) This study identifies those genes that are dependent on EcR for their proper regulation at the onset of metamorphosis in Drosophila melanogaster. Keywords: Nuclear receptor gene regulation

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS2675

Platform:

GPL72

18 Samples

Download data: CEL

(Submitter supplied) To identify 20E-regulated genes, wandering third instar larvae were dissected and their organs were cultured in the presence of either no hormone, 20E alone, cycloheximide alone, or 20E plus cycloheximide for six hours. Keywords: Hormone response

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS2674

Platform:

GPL72

12 Samples

Download data: CEL

(Submitter supplied) This study identifies genes that alter their expression in synchrony with the late third instar and prepupal pulses of 20E. Keywords: time course

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS2673

Platform:

GPL72

27 Samples

Download data: CEL

Analysis of ecdysone receptor (EcR) depleted animals 4 hours before to 4 hours after the start of pupariation. EcR is part of receptor complex for 20-hydroxyecdysone (20E), a hormone that triggers developmental transitions in insects. Results provide insight into the mechanisms regulated by 20E.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 development stage, 2 protocol, 3 time sets

Platform:

GPL72

Series:

GSE3069

18 Samples

Download data: CEL

Analysis of cultured larval organs treated with 20-hydroxyecdysone (20E) alone or in combination with cycloheximide to distinguish primary responses to 20E signal. Organs dissected from third instar larvae. Results provide insight into the molecular events triggered by 20E during insect development.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 4 agent sets

Platform:

GPL72

Series:

GSE3060

12 Samples

Download data: CEL

Analysis of animals before and after pupariation. A pulse of steroid hormone 20-hydroxyecdysone (20E) at late 3rd instar triggers puparium formation; a second 20E pulse after pupariation marks the prepupal-to-pupal transition. Results provide insight into the molecular mechanisms of 20E signaling.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 3 development stage, 9 time sets

Platform:

GPL72

Series:

GSE3057

27 Samples

Download data: CEL

(Submitter supplied) We used cell-type-specific ribosome profiling (Ribo-tag) to study the impacts of aging and oxidative stress on the expression of actively translated mRNA in adult Drosophila oenocytes. Polysome associated mRNAs from oenocyte were extracted from young flies and aged flies, treated with water or paraquat. Restults provide insight into aging mechanism and tissue specific response to stress in oenocyte.

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23323

12 Samples

Download data: XLSX