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In cell Mutational Interference Mapping Experiment (in cell MIME) identifies the 5’ PolyA signal as a dual regulator of HIV-1 genomic RNA production and packaging

(Submitter supplied) Non-coding RNA regulatory elements are important for viral replication, making them promising targets for therapeutic intervention. However, regulatory RNA is challenging to detect and characterise using classical structure-function assays. Here, we present in cell Mutational Interference Mapping Experiment (in cell MIME) as a way to define RNA regulatory landscapes at single nucleotide resolution under native conditions. more...
Organism:
Human immunodeficiency virus 1
Type:
Other
Platform:
GPL20319
27 Samples
Download data: TXT
Series
Accession:
GSE109386
ID:
200109386

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