GEO DataSets

(Submitter supplied) We compared the transcriptomes of Amphioxus (Branchiostoma lanceolatum) control and SU5402 treated embryos to define putative FGF signalling pathway target genes during somitogenesis. Embryos were treated with 50µM of SU5402 from 5.5hpf to 8.5hpf, 11.5hpf, and 14.5hpf or from 15hpf to 18hpf, 21hpf, 24hpf. Total RNA was extracted from control and treated embryos.

Organism:

Branchiostoma lanceolatum

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL25775 GPL20177

24 Samples

Download data: FASTA, TXT

(Submitter supplied) During the development of the vertebrate embryo, segmented structures called somites are periodically formed from the presomitic mesoderm (PSM), and give rise to the vertebral column. While somite formation has been studied in several animal models, it is less clear how well this process is conserved in humans. Recent progress has made it possible to study aspects of human paraxial mesoderm development such as the human segmentation clock in vitro using human pluripotent stem cells (hPSCs), however, somite formation has not been observed in these monolayer cultures. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24676

4 Samples

Download data: MTX, TSV

(Submitter supplied) What genomic changes led to the origin of vertebrates remains a mystery. On the one hand, animal evolution is thought to be driven mostly by changes in the cis-regulatory regions of a shared conserved and toolkit of developmental genes. On the other hand, vertebrates experienced two rounds of whole genome duplication (WGD) that increased their gene repertoire, particularly of regulatory genes controlling embryo development. more...

Organism:

Danio rerio

Type:

Other

Platform:

GPL14875

83 Samples

Download data: BEDGRAPH

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Branchiostoma lanceolatum; Danio rerio; Oryzias latipes

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

7 related Platforms

217 Samples

Download data: BED, BEDGRAPH, TXT

(Submitter supplied) What genomic changes led to the origin of vertebrates remains a mystery. On the one hand, animal evolution is thought to be driven mostly by changes in the cis-regulatory regions of a shared conserved and toolkit of developmental genes. On the other hand, vertebrates experienced two rounds of whole genome duplication (WGD) that increased their gene repertoire, particularly of regulatory genes controlling embryo development. more...

Organism:

Branchiostoma lanceolatum; Danio rerio; Oryzias latipes

Type:

Expression profiling by high throughput sequencing

4 related Platforms

81 Samples

Download data: TXT

(Submitter supplied) What genomic changes led to the origin of vertebrates remains a mystery. On the one hand, animal evolution is thought to be driven mostly by changes in the cis-regulatory regions of a shared conserved and toolkit of developmental genes. On the other hand, vertebrates experienced two rounds of whole genome duplication (WGD) that increased their gene repertoire, particularly of regulatory genes controlling embryo development. more...

Organism:

Branchiostoma lanceolatum

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24206

7 Samples

Download data: BEDGRAPH

(Submitter supplied) What genomic changes led to the origin of vertebrates remains a mystery. On the one hand, animal evolution is thought to be driven mostly by changes in the cis-regulatory regions of a shared conserved and toolkit of developmental genes. On the other hand, vertebrates experienced two rounds of whole genome duplication (WGD) that increased their gene repertoire, particularly of regulatory genes controlling embryo development. more...

Organism:

Branchiostoma lanceolatum; Oryzias latipes; Danio rerio

Type:

Genome binding/occupancy profiling by high throughput sequencing

4 related Platforms

29 Samples

Download data: BED

(Submitter supplied) What genomic changes led to the origin of vertebrates remains a mystery. On the one hand, animal evolution is thought to be driven mostly by changes in the cis-regulatory regions of a shared conserved and toolkit of developmental genes. On the other hand, vertebrates experienced two rounds of whole genome duplication (WGD) that increased their gene repertoire, particularly of regulatory genes controlling embryo development. more...

Organism:

Branchiostoma lanceolatum

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL24206

17 Samples

Download data: BED

(Submitter supplied) To be able to fully comprehend the contribution of the epigenome to embryonic development, it is important to understand how various components of the epigenome evolved. To date, a number of studies have thoroughly described various epigenetic mechanisms in both vertebrates and invertebrates, however there is currently a lack of high resolution epigenomic data corresponding to animals that form the invertebrate-vertebrate boundary. more...

Organism:

Branchiostoma lanceolatum

Type:

Methylation profiling by high throughput sequencing

Platforms:

GPL25186 GPL23852

10 Samples

Download data: TSV, TXT

(Submitter supplied) Signaling pathways control a large number of gene regulatory networks (GRNs) during animal development, acting as major tools for body plan formation [Pires-daSilva & Sommer, Nat. Rev. Genet. 4, 39-49 (2003)]. Remarkably, in contrast to the large number of transcription factors present in animal genomes, only a few of these pathways operate during development [Sanz-Ezquerro, Münsterberg & Stricker, Front. more...

Organism:

Xenopus tropicalis; Ptychodera flava

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL31012 GPL31011

18 Samples

Download data: TSV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Branchiostoma lanceolatum; Xenopus tropicalis; Danio rerio; Ptychodera flava

Type:

Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

4 related Platforms

75 Samples

Download data: TSV, TXT

(Submitter supplied) Signaling pathways control a large number of gene regulatory networks (GRNs) during animal development, acting as major tools for body plan formation. Remarkably, in contrast to the large number of transcription factors present in animal genomes, only a few of these pathways operate during development. Moreover, most of them are largely conserved along metazoan evolution. How evolution has generated a vast diversity of animal morphologies with such a limited number of tools is still largely unknown. more...

Organism:

Danio rerio; Branchiostoma lanceolatum

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL21741 GPL24210

33 Samples

Download data: TXT

(Submitter supplied) Signaling pathways control a large number of gene regulatory networks (GRNs) during animal development, acting as major tools for body plan formation. Remarkably, in contrast to the large number of transcription factors present in animal genomes, only a few of these pathways operate during development. Moreover, most of them are largely conserved along metazoan evolution. How evolution has generated a vast diversity of animal morphologies with such a limited number of tools is still largely unknown. more...

Organism:

Branchiostoma lanceolatum; Danio rerio

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL21741 GPL24210

24 Samples

Download data: BED