Similar studies for GEO DataSets (Select 200124722) - GEO DataSets

(Submitter supplied) The vitamin D receptor (VDR) has been knocked out in monocytic THP-1 cells after stimulation of ko and control cells with the the natural VDR ligand 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), quadruplicate mRNA-seq has been performed

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
32 Samples

Download data: XLSX

Series

Accession:: GSE157514

ID:: 200157514

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001572096.

ETS1 ChIP-seq in human monocytic THP-1 cells

(Submitter supplied) ChIP-seq for ETS1 in THP-1 cells after stimulation with the the natural VDR ligand 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
4 Samples

Download data: TDF

Series

Accession:: GSE157209

ID:: 200157209

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001240327.

Effects of vitamin D on CEBPA binding in THP-1 cells

(Submitter supplied) Three independent repeats of ChIP-seq or ChIPmentation with THP-1 cells after treatment with either 1,25(OH)2D3 (VD) or control (EtOH) using antibody against CEBPA (3 time points).

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
18 Samples

Download data: TDF, TXT

Series

Accession:: GSE124032

ID:: 200124032

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001195568.

The pioneer factor CEBPA modulates vitamin D signaling

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
43 Samples

Download data: BED, TDF, TXT

Series

Accession:: GSE119556

ID:: 200119556

PubMed Full text in PMC Similar studies

Select item 2001195559.

Effects of vitamin D on histone modification H3K4me3 in THP-1 cells

(Submitter supplied) Three independent repeats of ChIP-seq from THP-1 after 2h and 8h treatment with 1,25D or EtOH (control), using antibody against histone marker H3K4me3.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
13 Samples

Download data: BED, TDF

Series

Accession:: GSE119555

ID:: 200119555

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20011955110.

Effects of transcription factor CEBPA knockdown on vitamin D target gene regulation in THP-1 cells

(Submitter supplied) Three independent repeats of siRNA knockdown of CEBPA, followed by 24h vitamin D treatment, RNA extraction and RNA-seq.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
12 Samples

Download data: CSV

Series

Accession:: GSE119551

ID:: 200119551

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20010785111.

Effects of vitamin D on histone modifications H3K27ac and H3K4me3 in THP-1 cells

(Submitter supplied) Three independent repeats of ChIP-seq from THP-1 after 24h treatment with 1,25D or EtOH (control), using antibodies against histone markers H3K27ac and H3K4me3

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
13 Samples

Download data: TDF

Series

Accession:: GSE107851

ID:: 200107851

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008943112.

VDR ChIP-seq in human monocytic THP-1 cells

(Submitter supplied) ChIP-seq for VDR in THP-1 cells after stimulation with the the natural VDR ligand 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
12 Samples

Download data: TDF

Series

Accession:: GSE89431

ID:: 200089431

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006996213.

CTCF ChIP-seq in human monocytic THP-1 cells with replicates (4)

(Submitter supplied) ChIP-seq for the insulator protein CTCF in THP-1 cells after stimulation with the the natural VDR ligand 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL9115
9 Samples

Download data: TDF

Series

Accession:: GSE69962

ID:: 200069962

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006930314.

1,25(OH)2D3 time course in THP-1 cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL9115
35 Samples

Download data: TDF

Series

Accession:: GSE69303

ID:: 200069303

PubMed Full text in PMC Similar studies

Select item 20006929715.

FAIRE-seq 1,25(OH)2D3 time course in THP-1 cells

(Submitter supplied) Assessment of regions of open chromatin by FAIRE-seq in THP-1 cells treated with 1,25(OH)2D3 for 0-48 h

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL9115
14 Samples

Download data: TDF

Series

Accession:: GSE69297

ID:: 200069297

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006928416.

RNA-seq 1,25(OH)2D3 time course in THP-1 cells

(Submitter supplied) gene expression profiling by RNA-seq in THP-1 cells treated with 1,25(OH)2D3 for 2.5-24 h

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL9115
18 Samples

Download data: DIFF, TDF

Series

Accession:: GSE69284

ID:: 200069284

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20012418017.

RNA-sequencing across three matched tissues highlights gene expression signatures in COPD

(Submitter supplied) Multiple gene expression studies have been performed separately in peripheral blood, lung, and airway tissues to study COPD. We performed RNA-sequencing gene expression profiling of large-airway epithelium, alveolar macrophage and peripheral blood samples from the same set of COPD cases and controls from the COPDGene study who underwent bronchoscopy at a single center. Using statistical and gene set enrichment approaches, we sought to improve the understanding of COPD by studying gene sets and pathways across these tissues, beyond the individual genomic determinants.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
63 Samples

Download data: TSV

Series

Accession:: GSE124180

ID:: 200124180

PubMed Full text in PMC Similar studies

Select item 20008876818.

Identification of PPARG regulated genes in human GM-CSF-primed monocyte-derived macrophages

(Submitter supplied) Identification of PPARG regulated genes in human GM-CSF polarized monocyte-derived macrophages by siRNA knock-down approaches.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL21185
6 Samples

Download data: TXT

Series

Accession:: GSE88768

ID:: 200088768

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001389619.

Smoking-dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of COPD

(Submitter supplied) Background: When exposed to specific stimuli, macrophages exhibit distinct activation programs, M1 and M2 polarization, that define macrophage function as inflammatory/immune effectors or anti-inflammatory/tissue remodeling cells, respectively. Due to their position on the lung epithelial surface, alveolar macrophages (AM) directly interact with environmental stimuli such as cigarette smoke, the major risk factor for the development of chronic obstructive pulmonary disease (COPD). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
70 Samples

Download data: CEL, CHP

Series

Accession:: GSE13896

ID:: 200013896

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008729220.

Transcriptomic analysis of lung tissue from cigarette smoke induced emphysema murine models and human COPD show shared and distinct pathways

(Submitter supplied) Although cigarette smoke (CS) is the primary risk factor for COPD, the underlying molecular mechanisms for the significant variability in developing COPD in response to CS are incompletely understood. We performed lung gene expression profiling of two different wild-type murine strains (C57BL/6J, NZW/LacJ) and two genetic models with mutations in COPD GWAS genes (HHIP, FAM13A) after 6 months of chronic CS exposure and compared the results to human COPD lung tissues. more...