Similar studies for GEO DataSets (Select 200135435) - GEO DataSets

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Items: 4

Select item 2001354351.

The Thermus thermophilus DEAD-box protein Hera is a general RNA chaperone and plays a key role in tRNA metabolism

(Submitter supplied) RNA helicases catalyze the ATP-dependent destabilization of RNA duplexes. DEAD-box helicases share a helicase core that mediates ATP binding and hydrolysis, RNA binding and unwinding. Most members of this family contain domains flanking the core that can confer RNA substrate specificity and guide the helicase to a specific RNA. However, the in vivo RNA substrates of most helicase are currently not defined. more...

Organism:: Thermus thermophilus HB27

Type:: Expression profiling by high throughput sequencing

Platform:: GPL27012
8 Samples

Download data: BED, BW

Series

Accession:: GSE135435

ID:: 200135435

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001446472.

SELEX and ChIP/CLIP-Seq identification of nucleic acid sequences bound by the DDX43 KH domain (89 aa)

(Submitter supplied) SELEX (systematic evolution of ligands by exponential enrichment), chromatin immunoprecipitation (ChIP)-seq, and crosslinking immunoprecipitation (CLIP)-seq showed that the DDX43 KH domain binds C/T rich DNA and U rich RNA.

Organism:: synthetic construct; Homo sapiens

Type:: Other; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL16791 GPL19604
10 Samples

Download data: BEDGRAPH, CSV

Series

Accession:: GSE144647

ID:: 200144647

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2002288283.

The DEAD-box RNA helicase Ded1 is a translation-elongation factor

(Submitter supplied) DEAD-box RNA helicases are ATP-dependent RNA binding proteins and RNA-dependent ATPases that possess weak, nonprocessive unwinding activity in vitro, but they can form long-lived complexes on RNAs when the ATPase activity is inhibited. Ded1 is a yeast DEAD-box protein, the functional ortholog of mammalian DDX3, that is considered important for the scanning efficiency of the 48S pre-initiation complex ribosomes to the AUG start codon. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing; Other

Platform:: GPL19756
6 Samples

Download data: TXT

Series

Accession:: GSE228828

ID:: 200228828

PubMed Full text in PMC Similar studies

Select item 2001870214.

Small RNA sequencing of in vitro Angiogenin-hydrolyzed tRNAs

(Submitter supplied) Specific environmental insults cause the limited fragmentation of transfer RNAs (tRNAs) into tRNA-derived small RNAs (tsRNAs), which have been implicated in a wide range of biological processes. tRNA fragmentation results from endonucleolytic activities targeting single-stranded tRNA regions. However, how a tRNA with a single hydrolyzed phosphodiester bond in the anticodon loop (‘nicked’ tRNA) gives rise to distinct tsRNAs remains poorly understood. more...