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Links from GEO DataSets

Items: 2

1.

Diet-induced obesity promotes infection by impairment of the innate antimicrobial defense function of dermal adipocyte progenitors

(Submitter supplied) We report the transcriptomes of single cells isolated from whole skin of wild type B6 male mice fed a standard or 60% high fat diet 48-hours after mock- or S. aureus-infection.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
4 Samples
Download data: MTX, TSV
Series
Accession:
GSE150729
ID:
200150729
2.

Age-related loss of innate immune antimicrobial function of dermal fat is mediated by TGFβ

(Submitter supplied) Dermal fibroblasts (dFB) resist infection by locally differentiating into adipocytes and producing the antimicrobial peptide cathelicidin in response to S. aureus. We found that neonatal dFB were highly adipogenic whereas this adipogenic function was lost during adulthood. To better understand the molecular nature of the change in antimicrobial and adipogenic function of dFB, we profiled the transcriptomes of primary dFB isolated at different ages by RNA-seq. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL19057
15 Samples
Download data: TXT
Series
Accession:
GSE121460
ID:
200121460

Supplemental Content

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