GEO DataSets

(Submitter supplied) Adipocyte-specific expression of Na,K-ATPase signaling antagonist, NaKtide, has been shown to ameliorate the pathophysiological consequences of obesity and improve diseased phenotype. Recent studies have established that the release of adipocytokines and other bioactive mediators in obesity contributes to neurodegeneration. This study utilizes a mechanistic approach and characterizes the hippocampal transcriptome in comparison with transcriptomic changes in liver, visceral and subcutaneous adipose tissue. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13112

42 Samples

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(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13112

102 Samples

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(Submitter supplied) Adipocyte-specific expression of Na,K-ATPase signaling antagonist, NaKtide, has been shown to ameliorate the pathophysiological consequences of obesity and improve diseased phenotype. Recent studies have established that the release of adipocytokines and other bioactive mediators in obesity contributes to neurodegeneration. This study utilizes a mechanistic approach and characterizes the hippocampal transcriptome in comparison with transcriptomic changes in liver, visceral and subcutaneous adipose tissue. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13112

60 Samples

Download data: CSV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18480

54 Samples

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(Submitter supplied) We performed expression profiling by RNA-Seq on 3T3 mouse pre-adipocyte cells. Cells were divided into six groups of five replicates each and were treated with either control (DMSO), Indoxyl Sulphate, or Oxidative LDL, either with or without pNaKtide (NaK).

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18480

30 Samples

Download data: CSV

(Submitter supplied) We performed expression profiling by RNA-Seq on C57BL6 mice at 10 weeks of age. Mice were divided into four groups and either underwent partial nephrectomy (PNx) or sham (CTR) operation, and were adminstered either pNaKtide (NaK) or GFP.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18480

24 Samples

Download data: CSV