GEO DataSets

(Submitter supplied) To explore proteomic and transcriptomic changes in rat model of silicosis, transcriptomic analysis by microarray and tandem mass tags (TMT)-based proteomic analysis were performed to reveal the expression of mRNAs and proteins in lung tissues. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were applied to analyze the alterated genes and proteins. The integrated analysis was performed between transcriptome and proteome. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL25290

12 Samples

Download data: TXT

(Submitter supplied) Identification of molecular target(s) and mechanism(s) of silica-induced pulmonary toxicity is important for the intervention and/or prevention of diseases associated with occupational exposure to crystalline silica. Rats were exposed to crystalline silica by inhalation (15 mg/m3, 6 h/day, 5 days) and global gene expression profile was determined in the lungs by microarray analysis at 1, 2, 4, 8, and 16 weeks following termination of silica exposure. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL6101

60 Samples

Download data: TXT

(Submitter supplied) We established the ketamine-induced cystitis (KIC) models in female Sprague-Dawley rats. The bladder of the ketamine group and the control group were obtained to perform transcriptome analysis.

Organism:

Rattus norvegicus

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL18694

6 Samples

Download data: XLS

(Submitter supplied) PTEN Harmatoma Tumor Syndrome is a collection of clinical diagnosis with patients harbouring germline mutation in the PTEN gene. Most affected individuals have extreme macrocephaly and autism spectrum disorders were diagnosed in ~10% of the patients. However, the underpinning molecular mechanisms are not fully defined. The aim of this study is to compare the transcriptomic profiles of somatosensory cortices from Pten+/- and wild-type littermates (C57Bl6/J) of female and male at P30 and P42, primary neural cells, neuroprogenitor cells (NPCs), cortical astrocytes (PCA) and cortical neurons (PCN) from C57Bl6/J mice, with wild-type (WT as control for Pten+/- or CTRL as control for Nes-KO), heterozygous (Pten+/-)and complete knockout of Pten (Nes-KO). more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL21273 GPL17021 GPL21103

59 Samples

Download data: CSV

(Submitter supplied) Effect of TGFb1, TNFa, IL6-IL6R, IL1b on gene expression in Mouse Embryonnic Fibrobroblasts (3T3) using RNA microarrays.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL21810

15 Samples

Download data: TXT