Similar studies for GEO DataSets (Select 200242431) - GEO DataSets

(Submitter supplied) Heterochromatin domains defined by distinct histone methylation patterns are a major feature of mammalian genomes. Epigenetic pathways ensure stable heterochromatin inheritance through cell division to prevent the expression of lineage-inappropriate genes and defects in this process can lead to many diseases including cancer. Previous studies have shown that heterochromatin maintenance requires a critical threshold of methylated histones, but how modified parental histones are transferred to daughter strands during DNA replication is unclear. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20584 GPL16192
66 Samples

Download data: BEDGRAPH

Series

Accession:: GSE242353

ID:: 200242353

PubMed Similar studies

Select item 2001627015.

A critical density of histone H3 lysine 9 tri-methylation is required for propagation of heterochromatin and epigenetic inheritance

(Submitter supplied) Occupancy profiling of myc-tagged Raf1 protein in fission yeast. Occupancy profiling of lysine 9 dimethylated and trimethylated histone H3 in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by array

Platform:: GPL6503
28 Samples

Download data: TXT

Series

Accession:: GSE162701

ID:: 200162701

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001844666.

Histone deacetylation primes chromatin to preserve epigenetic memory for self-propagation of heterochromatin domains

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20584 GPL6503
4 Samples

Download data: BEDGRAPH, TXT

Series

Accession:: GSE184466

ID:: 200184466

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001029057.

Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability

(Submitter supplied) Histone H3 lysine 9 methylation (H3K9me) mediates heterochromatic gene silencing and is important for genome stability and the regulation of gene expression. The establishment and epigenetic maintenance of heterochromatin involve the recruitment of H3K9 methyltransferases to specific sites on DNA, followed by the recognition of pre-existing H3K9me by the methyltransferase and methylation of proximal histone H3. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17225
111 Samples

Download data: TDF

Series

Accession:: GSE102905

ID:: 200102905

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000834958.

A transcriptionally permissive histone H3 lysine 9 methylation state enables RNAi-mediated heterochromatin assembly

(Submitter supplied) Heterochromatic DNA domains play important roles in the regulation of gene expression and maintenance of genome stability by silencing repetitive DNA elements and transposons. In organisms ranging from fission yeast to mammals, heterochromatin assembly at DNA repeats involves the activity of small noncoding RNAs (sRNAs) associated with the RNA interference (RNAi) pathway. Typically, sRNAs, originating from long noncoding RNAs transcribed from DNA repeats, guide Argonaute-containing effector complexes to complementary nascent RNAs to initiate histone H3 lysine 9 di- and tri-methylation (H3K9me2 and H3K9me3, respectively) and heterochromatin formation. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13988
71 Samples

Download data: TDF

Series

Accession:: GSE83495

ID:: 200083495

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001746419.

The histone chaperone FACT facilitates heterochromatin spreading through regulation of histone turnover and H3K9 methylation states

(Submitter supplied) Heterochromatin formation requires several steps involving: nucleation followed by spreading of large, silent domains and its faithful re-establishment and maintenance after each replication cycle. The essential histone chaperone FACT has been implicated in heterochromatin silencing, however, little is known about the specificity of FACT in this process. Here, by applying single cell assays, ChIP and genetics, we show that FACT mutants have defects in the spreading of heterochromatin at subtelomeres and mating type locus in fission yeast. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13988
8 Samples

Download data: BW

Series

Accession:: GSE174641

ID:: 200174641

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20014107010.

Nuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance [ChIP-seq]

(Submitter supplied) Occupancy profiling of GFP-tagged Rix1 protein in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL16192
5 Samples

Download data: BEDGRAPH

Series

Accession:: GSE141070

ID:: 200141070

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20013286511.

Nuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL8908 GPL16192 GPL6503
33 Samples

Download data: BEDGRAPH, TXT

Series

Accession:: GSE132865

ID:: 200132865

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20013286212.

Nuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance [ChIP-chip_C300]

(Submitter supplied) Occupancy profiling of GFP-tagged Rix1, Las1, Ipi1, Crb3 proteins in fission yeast. Occupancy profiling of lysine 9 trimethylated histone H3 in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
22 Samples

Download data: TXT

Series

Accession:: GSE132862

ID:: 200132862

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20013279713.

Nuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance [ChIP-chip_C50]

(Submitter supplied) Occupancy profiling of FLAG-tagged H3 in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL8908
6 Samples

Download data: TXT

Series

Accession:: GSE132797

ID:: 200132797

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004537814.

HDAC mediated suppression of histone turnover promotes epigenetic stability of heterochromatin

(Submitter supplied) Analysis of histone H3 turnover in wild-type and mutant fission yeast cells by using MNase-ChIP-chip

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL11244 GPL16854
13 Samples

Download data: TXT

Series

Accession:: GSE45378

ID:: 200045378

PubMed Full text in PMC Similar studies

Select item 20009327315.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [HU + BrdU IP]

(Submitter supplied) BrdU profiling of replication activity in synchronous culture of fission yeast. Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome variation profiling by genome tiling array

Platform:: GPL6503
2 Samples

Download data: TXT

Series

Accession:: GSE93273

ID:: 200093273

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008890416.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL8908 GPL6503
20 Samples

Download data: TXT

Series

Accession:: GSE88904

ID:: 200088904

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008890317.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [BrdU IP]

(Submitter supplied) BrdU profiling of replication activity in hydroxyurea treated synchronous culture of fission yeast. Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
4 Samples

Download data: TXT

Series

Accession:: GSE88903

ID:: 200088903

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008890218.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [H3K9me2 ChIP]

(Submitter supplied) H3K9me2 profiles and Fft3 occupancy in fission yeast. Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
7 Samples

Download data: TXT

Series

Accession:: GSE88902

ID:: 200088902

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008890119.

Snf2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance of Heterochromatin and Proper Replication of the Genome [H3-FLAG ChIP]

(Submitter supplied) H3-FLAG incorporation in Schizosaccharomyces pombe Heterochromatin can be epigenetically inherited in cis, leading to stable maintenance of gene expression states. However, the mechanisms underlying heterochromatin inheritance remain unclear. Here we identify Fft3, a homolog of the mammalian SMARCAD1 Snf2 chromatin remodeler, as a factor uniquely required for heterochromatin inheritance, rather than for de novo assembly. more...