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Links from GEO DataSets

Items: 20

1.
Full record GDS2281

Uniparental duplication of chromosome 7 regions effect on embryo and newborn brain (MG-430B)

Analysis of embryos and brains of newborns with maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps. Results provide insight into the extent and distribution of imprinted genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 tissue sets
Platform:
GPL340
Series:
GSE4870
4 Samples
Download data: CEL, EXP
2.

Expression data from T65H translocation mice

(Submitter supplied) Tissue-specific comparison of gene expression levels in T65H translocation mice, either with or without uniparental duplications of Chrs 7 & 11. Identification of highly differentially expressed transcripts. Keywords: genetic modification
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS2281 GDS2282 GDS2283 GDS2284 GDS2285
5 related Platforms
45 Samples
Download data: CEL, EXP
Series
Accession:
GSE4870
ID:
200004870
3.
Full record GDS2285

Uniparental duplication of chromosome 7 regions effect on various tissues (MG-U74C)

Analysis of various tissues from animals bearing maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps proximal and distal to the breakpoint. Results provide insight into the extent and distribution of imprinted genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 genotype/variation, 4 tissue sets
Platform:
GPL83
Series:
GSE4870
11 Samples
Download data: CEL, EXP
4.
Full record GDS2284

Uniparental duplication of chromosome 7 regions effect on various tissues (MG-U74B)

Analysis of various tissues from animals bearing maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps proximal and distal to the breakpoint. Results provide insight into the extent and distribution of imprinted genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 genotype/variation, 5 tissue sets
Platform:
GPL82
Series:
GSE4870
13 Samples
Download data: CEL, EXP
5.
Full record GDS2283

Uniparental duplication of chromosome 7 regions effect on embryo and newborn brain (MG-430A)

Analysis of embryos and brains of newborns with maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps. Results provide insight into the extent and distribution of imprinted genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 tissue sets
Platform:
GPL339
Series:
GSE4870
4 Samples
Download data: CEL, EXP
6.
Full record GDS2282

Uniparental duplication of chromosome 7 regions effect on various tissues (MG-U74A)

Analysis of various tissues from animals bearing maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps proximal and distal to the breakpoint. Results provide insight into the extent and distribution of imprinted genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 genotype/variation, 5 tissue sets
Platform:
GPL81
Series:
GSE4870
13 Samples
Download data: CEL, EXP
7.

Mouse embryonic heart transcriptomic response to Ddc (Ddc_exon1a isoform) ablation

(Submitter supplied) Analysis of gene expression in mouse E15.5 embryonic heart tissue, either wildtype, Ddc-/+ (maternal transmission of Ddc^Gt(OST129277)Lex knockout allele), Ddc+/- (paternal transmission), or Ddc-/-.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
12 Samples
Download data: IDAT, TXT
Series
Accession:
GSE87595
ID:
200087595
8.

Methylation screening of reciprocal genome-wide UPDs identifies novel human specific imprinted genes

(Submitter supplied) Utilizing reciprocal genome-wide uniparental disomy samples presenting with Beckwith-Wiedemann and Silver-Russell syndrome-like phenotypes, we have analyzed ~0.1% of CpG dinucleotides present in the human genome for imprinted differentially methylated regions (DMRs) using the Illumina Infinium HumanMethylation27 BeadChip microarray. This approach identified 15 imprinted DMRs associated with previously characterized imprinted domains, and confirmed the maternal methylation of the RB1 DMR. more...
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
15 Samples
Download data: TXT
Series
Accession:
GSE28525
ID:
200028525
9.

Allele-specific Methylation of Human Placental Tissue

(Submitter supplied) In this study, we screened human placental samples for allele-specific methylation and subsequently novel imprinted genes associated with these regions. We used reduced representation bisulfite sequencing to identify partially methylated CpG islands (CGIs) in the human placental genome. We were able to delineate potential candidates for allele-specific methylation based on the calculation of a concordance statistic. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL10999
10 Samples
Download data: TXT
Series
Accession:
GSE40955
ID:
200040955
10.

Methylation profiling in individuals with uniparental disomy identifies novel differentially methylated regions on chromosome 15

(Submitter supplied) Methylation profiles of chr12-16 were generated by meDIP and array hybridisation in 3 cases with maternal uniparental disomy of chromosome 15, and three cases of paternal uniparental disomy of chromosome 15. Comparison of these profiles reveals differentially methylated (imprinted) regions on chromosome 15.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL10483
12 Samples
Download data: PAIR
Series
Accession:
GSE22188
ID:
200022188
11.

A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by genome tiling array
26 related Platforms
76 Samples
Download data: TXT
Series
Accession:
GSE21662
ID:
200021662
12.

Methylation status in human sperm

(Submitter supplied) Genomic imprinting describes the expression of a subset of mammalian genes from one parental chromosome. The parent-of-origin specific expression of imprinted genes relies on DNA methylation of CpG-dinucleotides at differentially methylated regions (DMRs) during gametogenesis. We identified the paternally methylated DMR at human chromosome 2 near the imprinted ZDBF2 gene using a methylated-DNA immunoprecipitation-on-chip (meDIP-on-chip) method applied to DNA from sperm.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL9641
1 Sample
Download data: TXT
Series
Accession:
GSE18178
ID:
200018178
13.

Methylation status in AG- and PG-derived cells and sperm

(Submitter supplied) Genomic imprinting describes the expression of a subset of mammalian genes from one parental chromosome. The parent-of-origin specific expression of imprinted genes relies on DNA methylation of CpG-dinucleotides at differentially methylated regions (DMRs) during gametogenesis. We identified the paternally methylated DMRs at mouse chromosome 1 near the imprinted Zdbf2 gene using a methylated-DNA immunoprecipitation-on-chip (meDIP-on-chip) method applied to DNA from parthenogenetic (PG)- and androgenetic (AG)-derived cells and sperm. more...
Organism:
Mus musculus
Type:
Methylation profiling by genome tiling array
25 related Platforms
75 Samples
Download data: TXT
Series
Accession:
GSE18126
ID:
200018126
14.

Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15

(Submitter supplied) Gene expression profiling was performed on CNS tissue from neonatal mice carrying the T9H translocation and maternal or paternal duplication of proximal Chromosomes 7 and 15. Our analysis revealed the presence of two novel paternally expressed intergenic transcripts at the PWS/AS locus. The transcripts were termed Pec2 and Pec3 for paternally expressed in the CNS.Our analysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL340 GPL339
22 Samples
Download data: CEL, CHP
Series
Accession:
GSE12231
ID:
200012231
15.

Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430B)

(Submitter supplied) Gene expression profiling was performed on CNS tissue from neonatal mice carrying the T9H translocation and maternal or paternal duplication of proximal Chromosomes 7 and 15. Our analysis revealed the presence of two novel paternally expressed intergenic transcripts at the PWS/AS locus. The transcripts were termed Pec2 and Pec3 for paternally expressed in the CNS.Our analysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL340
8 Samples
Download data: CEL, CHP
Series
Accession:
GSE12230
ID:
200012230
16.

Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430A)

(Submitter supplied) Gene expression profiling was performed on CNS tissue from neonatal mice carrying the T9H translocation and maternal or paternal duplication of proximal Chromosomes 7 and 15. Our analysis revealed the presence of two novel paternally expressed intergenic transcripts at the PWS/AS locus. The transcripts were termed Pec2 and Pec3 for paternally expressed in the CNS.Our analysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
14 Samples
Download data: CEL, CHP
Series
Accession:
GSE12227
ID:
200012227
17.

A Novel Approach Identifies New Differentially Methylated Regions (DMRs) Associated with Imprinted Genes

(Submitter supplied) Imprinted genes are critical for normal human growth and neurodevelopment. We developed a strategy to identify new DNA differentially methylated regions (DMRs), a hallmark of imprinted genes. Using genome-wide methylation profiling, candidate DMRs were selected by identifying CpGs with putative allelic differential methylation in normal biparental tissues. In parallel, we looked for parent of origin-specific DNA methylation patterns in paternally derived human androgenetic complete hydatidiform mole (AnCHM), and maternally derived mature cystic ovarian teratoma (MCT). more...
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
26 Samples
Download data: TXT
Series
Accession:
GSE22091
ID:
200022091
18.

Maternal versus paternal uniparental disomy of Chr12 and Chr18: whole embryo and placenta

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
5 related Platforms
10 Samples
Download data: CEL, CHP
Series
Accession:
GSE10118
ID:
200010118
19.

Expression data from UPD18 mice

(Submitter supplied) Comparison of gene expression levels between matUPD18 and patUPD18 8.5 dpc whole embryo samples (maternal versus paternal uniparental disomy of Chr 18). Identification of highly differentially expressed transcripts. Keywords: genetic modification
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
2 Samples
Download data: CEL, CHP
Series
Accession:
GSE10085
ID:
200010085
20.

Expression data from UPD12 mice

(Submitter supplied) Comparison of gene expression levels between matUPD12 and patUPD12 15.5 dpc whole embryo or placenta samples (maternal versus paternal uniparental disomy of Chr 12). Identification of highly differentially expressed transcripts. Keywords: genetic modification
Organism:
Mus musculus
Type:
Expression profiling by array
4 related Platforms
8 Samples
Download data: CEL, CHP
Series
Accession:
GSE10081
ID:
200010081
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