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Links from GEO DataSets

Items: 5

1.
Full record GDS2379

Oligodendrocyte progenitor and oligodendrocyte comparison (RAE230A)

Analysis of FACS-purified A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes from the brains of postnatal day 7 Sprague Dawley males. Results provide insight into the mechanisms underlying oligodendrocyte maturation.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 development stage sets
Platform:
GPL341
Series:
GSE5940
9 Samples
Download data
2.

Gene Expression Profiling of Primary Rat Oligodendrocytes

(Submitter supplied) Oligodendrocytes undergo extensive changes as they differentiate from progenitors into myelinating cells. To better understand the molecular mechanisms underlying this transformation, we performed a comparative analysis using gene expression profiling of A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes. Cells were sort-purified ex vivo from postnatal rat brain using flow cytometry. Using Affymetrix microarrays, 1707 transcripts were identified with a more than twofold increase in expression inO4+oligodendrocytes. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Datasets:
GDS2379 GDS2380
Platforms:
GPL341 GPL342
18 Samples
Download data
Series
Accession:
GSE5940
ID:
200005940
3.
Full record GDS2380

Oligodendrocyte progenitor and oligodendrocyte comparison (RAE230B)

Analysis of FACS-purified A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes from the brains of postnatal day 7 Sprague Dawley males. Results provide insight into the mechanisms underlying oligodendrocyte maturation.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 development stage sets
Platform:
GPL342
Series:
GSE5940
9 Samples
Download data
4.

The oligodendrocyte "protrusiosome": Identification of compartmentalized enrichment of transcripts in newly-formed protrusions of oligodendrocyte precursor cells (OPC) by RNAseq

(Submitter supplied) Like neurons, oligodendrocytes (OL) are cells with elaborate morphology that probably require asymmetrical spatial regulation of biological processes. Formation of membrane protrusions is critical for OL development and interaction with axons. We hypothesized that the enrichment of specific mRNAs in protrusions of oligodendrocyte precursor cells (OPC) is important for morphological differentiation, thus having an impact in myelination. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14844
4 Samples
Download data: TXT
Series
Accession:
GSE106862
ID:
200106862
5.

A2B5/OTMP+ rat perineuronal oligodendrocytes

(Submitter supplied) Oligodendrocytes are cells from the central nervous system that can be grouped into precursors, myelin-forming, and non-myelinating perineuronal. The function of perineuronal oligodendrocytes is unknown; it was suggested that they can ensheath denuded axons. We tested this hypothesis. Using cell-specific tags, microarray technology and bioinformatics tools to identify gene expression differences between these subpopulations allowed us to capture the genetic signature of perineuronal oligodendrocytes. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platforms:
GPL341 GPL342
8 Samples
Download data: CEL
Series
Accession:
GSE11277
ID:
200011277
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