Similar studies for GEO DataSets (Select 241) - GEO DataSets

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Items: 3

Select item 2411.

Alveoli destruction time course

Temporal study of lung alveoli destruction induced by caloric restriction. Alveoli number and surface area are linked to oxygen consumption, and calorie restriction lowers oxygen consumption.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 protocol, 8 time sets

Platform:: GPL81
Series:: GSE478
24 Samples

Download data: CEL

DataSet

Accession:: GDS241

ID:: 241

Select item 2000004782.

Alveoli loss during caloric restriction time course

(Submitter supplied) Pulmonary alveoli are complex architectural units thought to undergo endogenous or pharmacologically induced programs of regeneration and degeneration. To study the molecular mechanism of alveoli loss mice were calorie restricted at different timepoints. Lungs were harvested and processed for RNA extraction. Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS241
Platforms:: GPL1261 GPL81
25 Samples

Download data: CEL

Series

Accession:: GSE478

ID:: 200000478

Select item 2001007013.

Lifelong calorie restriction and markers of colonic health in aging mice

(Submitter supplied) Diminishment of colonic health is associated with various age-related pathologies. Calorie restriction (CR) is an efficient strategy to increase healthy lifespan, although underlying mechanisms are not fully elucidated. Here we report the effects of lifelong CR on markers of colonic health in aging mice. We show that 30% energy reduction, as compared to a control (C) and moderate-fat (MF) diet, is associated with attenuated immune-related gene expression and lower levels of bile acids in the colon. more...