GEO DataSets

Analysis of primary cardiomyocyte cultures treated with eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA). EPA and DHA are n-3 polyunsaturated fatty acids (PUFAs). Results provide insight into the molecular basis of the cardioprotective effect of n-3 PUFAs.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, log2 ratio, 2 agent sets

Platform:

GPL890

Series:

GSE4327

4 Samples

Download data

(Submitter supplied) Despite the recognized protective effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in cardiovascular diseases, and the demonstration of the control of gene expression by polyunsaturated fatty acids (PUFAs), the effects of these n-3 fatty acids on the whole genoma has never been investigated in cardiac cells. Using rat arrays, the effects of Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) supplementation on the global gene expression profile were evaluated in cultured neonatal rat cardiomyocytes. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS2607

Platform:

GPL890

4 Samples

Download data

(Submitter supplied) Background and Aims: It is known that inflammatory processes are activated in heart failure, but the regulation of cytokines and their role in the pathogenesis of the disease are not well understood. To address this issue, we have performed microarray analysis of non-infarcted left ventricular tissue from mice at various time-points after myocardial infarction. Methods: Molecular alterations in myocardial tissue were measured 3, 5, 7 and 14 days after induced infarction by using cDNA microarrays. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3386

Platform:

GPL891

20 Samples

Download data

Analysis of non-infarcted left ventricular tissues from animals at various time points up to 14 days following myocardial infarction (MI). MI induced by ligating the left coronary artery. Results provide insight into the molecular pathogenesis of heart failure.

Organism:

Mus musculus

Type:

Expression profiling by array, log2 ratio, 4 time sets

Platform:

GPL891

Series:

GSE6580

20 Samples

Download data