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Links from GEO DataSets

Items: 4

1.
Full record GDS2687

Kruppel-like factor 15 deficient liver and skeletal muscle response to fasting

Analysis of livers and quadriceps muscles of Kruppel-like factor 15 (KLF15) null mutants after an overnight fast. KLF15 nulls develop hypoglycemia after fasting. Gluconeogenesis (GLC) is essential for preventing hypoglycemia during fasting. Results provide insight into the role of KLF15 in GLC.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 tissue sets
Platform:
GPL8321
Series:
GSE7137
16 Samples
Download data: CEL, EXP
2.

Expression data from 18h-fasted WT versus KLF15-null mice: liver and quadriceps skeletal muscle

(Submitter supplied) We used microarray analysis to identify differences in gene expression levels, in liver and in quadriceps skeletal muscle, between 18h (overnight) fasted WT control and Kruppel-like factor 15 (KLF15)-null mice. Keywords: comparative expression analysis, fasted state
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2687
Platform:
GPL8321
16 Samples
Download data: CEL, EXP
Series
Accession:
GSE7137
ID:
200007137
3.

Expression data in liver of Lkb1KOlivad mice (hepatocyte-specific Lkb1 deficiency, KO) and control (WT) mice

(Submitter supplied) We used microarrays to investigate gene expression patterns in liver of hepatocyte-specific Lkb1 deficiency
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
6 Samples
Download data: CEL
Series
Accession:
GSE132536
ID:
200132536
4.

LKB1 and Notch deletion in mouse liver

(Submitter supplied) We characterize the phenotype of mice in which the deletion of Lkb1 has been targeted in the liver. Lack of Lkb1 in the liver results in bile duct paucity leading to cholestasis. This phenotype is similar to that obtained upon inactivation of Notch signaling in the liver. We test the hypothesis of a functional overlap between the Lkb1 and Notch pathways by gene expression profiling of livers deficent in Lkb1 or in the Notch mediator RbpJκ. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL17791
12 Samples
Download data: CEL
Series
Accession:
GSE75564
ID:
200075564
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