Similar studies for GEO DataSets (Select 2803) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from GEO DataSets

Items: 3

Select item 28031.

Fluoxetine effect on the hippocampus

Analysis of hippocampi from DBA/2J males chronically treated with the antidepressant (AD) fluoxetine (Flx). ADs promote the proliferation and survival of neurons in the adult hippocampus. Results provide insight into the molecular basis of the neuronal and behavioral responses to Flx treatment.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL1261
Series:: GSE6476
4 Samples

Download data: CEL, XML

DataSet

Accession:: GDS2803

ID:: 2803

Select item 2000064762.

Effect of chronic fluoxetine treatment on hippocampal gene expression

(Submitter supplied) Both the mechanism of action and the factors determining the behavioral response to antidepressants are unknown. It has been shown that antidepressant treatment promotes the proliferation and survival of hippocampal neurons via enhanced serotonergic signaling, but it is still unclear whether hippocampal neurogenesis is responsible for the behavioral response to antidepressants. Furthermore, a large subpopulation of patients fails to respond to antidepressant treatment due to presumed underlying genetic factors. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2803
Platform:: GPL1261
4 Samples

Download data: CEL, XML

Series

Accession:: GSE6476

ID:: 200006476

Select item 2000286443.

Gene Expression Data Following Chronic Vehicle or Fluoxetine Treatment in Thirty Mouse Inbred Lines

(Submitter supplied) In order to understand how biochemical and genetic differences correlate with treatment response, we measured depressive-like behavior, gene expression and the levels of thirty-six neurobiochemical analytes across a panel of genetically-diverse mouse inbred lines after chronic treatment with vehicle or fluoxetine. Neurobiochemical markers were chosen based on their putative molecular function within pathways proposed to underlie depression, which include neuronal transmission, HPA-axis regulation, and neuroimmune processes. more...