Similar studies for GEO DataSets (Select 3108) - GEO DataSets

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Items: 3

Select item 31081.

Alpha 2B-adrenoceptor deficient embryo and its placenta

Analysis of placentas of embryonic day E10.5 mutant embryos lacking alpha 2B-adrenoceptor (Adra2b). Adra2b-/- deficient embryos develop a defect in fetal and maternal vessel formation in the placenta labyrinth at E10.5. Results provide insight into the role of Adra2b in placental development.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE6909
6 Samples

Download data: CEL

DataSet

Accession:: GDS3108

ID:: 3108

Select item 2000069092.

Differential gene expression in placentae (E10.5) from adra2bKO and adra2bWT mice

(Submitter supplied) alpha2-adrenoceptors are essential presynaptic regulators of norepinephrine release from sympathetic nerves. Previous studies in mice with targeted deletions in the three alpha2-adrenoceptor genes have indicated that these receptors are essential for embryonic development. In the present study, we searched for the alpha2-adrenoceptor subtype(s) involved in placental development and its molecular mechanism using mice carrying targeted deletions in alpha2-adrenoceptor genes. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3108
Platform:: GPL1261
6 Samples

Download data: CEL

Series

Accession:: GSE6909

ID:: 200006909

Select item 2001571323.

Maternal Influenza A Virus Infection Restricts Fetal and Placental Growth and Adversely Affects the Fetal Thymic Transcriptome

(Submitter supplied) Maternal influenza A viral infections in humans are associated with low birth weight, increased risk of pre-term birth, stillbirth and congenital defects. To examine the effect of maternal influenza virus infection on placental and fetal growth, pregnant C57BL/6 mice were inoculated intranasally with influenza A virus A/CA/07/2009 pandemic H1N1 or PBS at E3.5, E7.5 or E12.5, and the placentae and fetuses collecgted and weighed at E18.5. more...