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Links from GEO DataSets

Items: 20

1.
Full record GDS3141

Colorectal mucosae from various regions of the large intestine

Analysis of colorectal mucosae from various regions of the normal large intestine. Results provide insight into the range of variation of gene expression in normal tissues.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 5 tissue sets
Platform:
GPL570
Series:
GSE9254
19 Samples
Download data: CEL
DataSet
Accession:
GDS3141
ID:
3141
2.

Normal human colorectal mucosa, cecum, ascending, transverse, sigmoid and rectum

(Submitter supplied) Normal human colorectal mucosa was sampled at points along the colon. Keywords: normal human tissue
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3141
Platform:
GPL570
19 Samples
Download data: CEL
Series
Accession:
GSE9254
ID:
200009254
3.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3643
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE10748
ID:
200010748
4.
Full record GDS3643

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 6 dose sets
Platform:
GPL1355
Series:
GSE10748
24 Samples
Download data: CEL
DataSet
Accession:
GDS3643
ID:
3643
5.

Gene Expression and Isoform Variation Analysis using Affymetrix Exon Arrays

(Submitter supplied) Background:Alternative splicing and isoform level expression profiling is an emerging field of interest within genomics. Splicing sensitive microarrays, with probes targeted to individual exons or exon-junctions, are becoming increasingly popular as a tool capable of both expression profiling and finer scale isoform detection. Despite their intuitive appeal, relatively little is known about the performance of such tools, particularly in comparison with more traditional 3’ targeted microarrays. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL5175 GPL5188
40 Samples
Download data: CEL
Series
Accession:
GSE13072
ID:
200013072
6.

Gene Expression and Isoform Variation: Exon-level Analysis

(Submitter supplied) Background:Alternative splicing and isoform level expression profiling is an emerging field of interest within genomics. Splicing sensitive microarrays, with probes targeted to individual exons or exon-junctions, are becoming increasingly popular as a tool capable of both expression profiling and finer scale isoform detection. Despite their intuitive appeal, relatively little is known about the performance of such tools, particularly in comparison with more traditional 3’ targeted microarrays. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5188
20 Samples
Download data: CEL
Series
Accession:
GSE13069
ID:
200013069
7.

Gene Expression and Isoform Variation: Gene-level Analysis

(Submitter supplied) Background:Alternative splicing and isoform level expression profiling is an emerging field of interest within genomics. Splicing sensitive microarrays, with probes targeted to individual exons or exon-junctions, are becoming increasingly popular as a tool capable of both expression profiling and finer scale isoform detection. Despite their intuitive appeal, relatively little is known about the performance of such tools, particularly in comparison with more traditional 3’ targeted microarrays. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5175
20 Samples
Download data: CEL
Series
Accession:
GSE13066
ID:
200013066
8.

Transcription profiling of biopsies from the descending colon of control subjects

(Submitter supplied) These samples were all taken from patients who underwent investigations including colonoscopy but where all tests were normal and the diagnosis of irritable bowel syndrome was reached. These observations have been used as references in studies of colonic gene expression in inflammatory bowel diseases
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
17 Samples
Download data: CEL
Series
Accession:
GSE11831
ID:
200011831
9.

Expression data for whole adult tissue; Drosophila males of seven species

(Submitter supplied) Co-expression of genes that physically cluster together is a common characteristic of eukaryotic transcriptomes. Identifying these groups of co-expressed genes is important to the functional annotation of genomes and understanding the evolutionary fates of the clustered genes. We used microarrays to measure gene expression in seven closely related Drosophila species, to identify domains clusters within a species of Drosophila (D. more...
Organism:
Drosophila mauritiana; Drosophila simulans; Drosophila yakuba; Drosophila santomea; Drosophila melanogaster; Drosophila sechellia; Drosophila teissieri
Type:
Expression profiling by array
Platform:
GPL72
48 Samples
Download data: CEL
Series
Accession:
GSE7873
ID:
200007873
10.

Human embryonic stem cells, differerentiated EBs and adult cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Macaca mulatta polyomavirus 1; Rattus norvegicus; Mus musculus; Human gammaherpesvirus 8; Homo sapiens; Macacine gammaherpesvirus 4
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL7088 GPL7089
38 Samples
Download data: GPR
Series
Accession:
GSE12250
ID:
200012250
11.

microRNA expression profiling among human embryonic stem cells, differerentiated EBs and adult cells

(Submitter supplied) Human embryonic stem (hES) cells have unique features: self-renewal ability and pluripotency. They can be continuously cultured in undifferentiated state and give rise to cells and tissues of all three germ layers. Thus hES cells provide a resource not only for cell replacement therapy but also for studying human developmental biology. We aimed to identify the unique signature of miRNAs in human embryonic stem cells. more...
Organism:
Rattus norvegicus; Macacine gammaherpesvirus 4; Mus musculus; Homo sapiens; Human gammaherpesvirus 8; Macaca mulatta polyomavirus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL7089
21 Samples
Download data: GPR
Series
Accession:
GSE12229
ID:
200012229
12.

Gene expression profiling among human embryonic stem cells, differerentiated EBs and adult cells

(Submitter supplied) Human embryonic stem (hES) cells have unique features: self-renewal ability and pluripotency. They can be continuously cultured in undifferentiated state and give rise to cells and tissues of all three germ layers. Thus hES cells provide a resource not only for cell replacement therapy but also for studying human developmental biology. However, much work needs to be done to understand the molecular mechanisms responsible for the maintenance of the undifferentiatiation state and the differentiation process of human embryonic stem cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL7088
17 Samples
Download data: GPR
Series
Accession:
GSE12228
ID:
200012228
13.

Definition, conservation and epigenetics of housekeeping and tissue-enriched genes

(Submitter supplied) Housekeeping genes (HKG) are constitutively expressed in all tissues while tissue-enriched genes (TEG) are expressed at a much higher level in a single tissue type than in others. HKGs serve as valuable experimental controls in gene and protein expression experiments, while TEGs tend to represent distinct physiological processes and are frequently candidates for biomarkers or drug targets. The genomic features of these two groups of genes expressed in opposing patterns may shed light on the mechanisms by which cells maintain basic and tissue-specific functions. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
26 related Platforms
564 Samples
Download data
Series
Accession:
GSE16546
ID:
200016546
14.

Definition, conservation and epigenetics of housekeeping and tissue-enriched genes

(Submitter supplied) Background Housekeeping genes (HKG) are constitutively expressed in all tissues while tissue-enriched genes (TEG) are expressed at a much higher level in a single tissue type than in others. HKGs serve as valuable experimental controls in gene and protein expression experiments, while TEGs tend to represent distinct physiological processes and are frequently candidates for biomarkers or drug targets. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3834
Platform:
GPL8217
42 Samples
Download data
Series
Accession:
GSE14938
ID:
200014938
15.
Full record GDS3834

Multiple normal tissues

Analysis of 42 normal tissues. Housekeeping genes (HKG) are constitutively expressed in all tissues; tissue-enriched genes (TEG) are more highly expressed in a single tissue type than in others. Results provide insight into mechanisms by which cells maintain basic and tissue-specific functions.
Organism:
Homo sapiens
Type:
Expression profiling by array, log10 ratio, 42 tissue sets
Platform:
GPL8217
Series:
GSE14938
42 Samples
Download data
16.

Identification of genes responsive to mild hyperthermia in human leukemia U937 cells

(Submitter supplied) The rationale underlying hyperthermia is the fact that temperatures over 42.5˚C are highly cytotoxic to tumor cells. On the other hand, although mild hyperthermia at a range from 39 to 41˚C alone did not induce cytotoxicity in tumor cells, mild hyperthermia is reported to show a synergism with radiotherapy and anti-cancer drugs. Here, the effects of mild hyperthermia (41˚C for 30 min) on the gene expression in human lymphoma U937 cells were investigated using by an Affymetrix GeneChip system. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3291
Platform:
GPL96
4 Samples
Download data: CEL, CHP
Series
Accession:
GSE10043
ID:
200010043
17.
Full record GDS3291

Myelomonocytic lymphoma U937 cell line response to mild hyperthermia

Analysis of myelomonocytic lymphoma U937 cells subjected to mild hyperthermia. Mild hyperthermia alone does not induce apoptosis but it does show a synergism with radiotherapy and anti-cancer drugs. Results provide insight into molecular mechanisms underlying cellular responses to mild hyperthermia.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL96
Series:
GSE10043
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3291
ID:
3291
18.

Effects of vasectomy on gene expression profiling along the human epididymis

(Submitter supplied) Worldwide, almost 100 millions men rely on vasectomy for male contraceptive purposes. Due to changes in their personal life, an increasing number of these men request surgical vasectomy reversal. Unfortunately, a significant proportion of these men remain infertile, despite the reestablishment of patent ducts, possibly due to epididymal damages caused by vasectomy. In animal models, vasectomy affects different epididymal physiological and biochemical parameters. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
9 Samples
Download data: CEL
Series
Accession:
GSE9731
ID:
200009731
19.

Region specific gene expression profiling along the human epididymis

(Submitter supplied) Analysis of the gene expression pattern in the caput, corpus and cauda epididymides of three donors of 26-50 years of age with no medical pathologies that could affect reproductive function. The data generated in this study demonstrate a region specific gene expression pattern along the human epididymis that seems to coincide with the morphological distinctive features of the excurrent duct. Keywords: Tissue compartements comparison
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
9 Samples
Download data: CEL
Series
Accession:
GSE7808
ID:
200007808
20.

Expression data from normal and CRC human peripheral blood samples

(Submitter supplied) The whole-genome oligonucleotide microarray analysis of peripheral blood samples can contribute to the determination of distant blood markers of local pathophysiological alterations in colorectal diseases. These markers can lead to alternative screening procedures. Keywords: whole genomic expression
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
30 Samples
Download data: CEL
Series
Accession:
GSE10715
ID:
200010715
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