GEO DataSets

Analysis of semilunar valves from neonates lacking the chemokine receptor CXCR7. Most animals lacking CXCR7 die at birth with ventricular septal defects and semilunar heart valve malformation. Results provide insight into the role of CXCR7 in heart valve development.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1261

Series:

GSE8710

4 Samples

Download data: CEL

(Submitter supplied) Cxcr7-/- mice die a few hours after birth. All of them display semilunar valves abnormalities, including bicuspid aortic or pulmonary valves. Those defects only become obvious before birth. Keywords: genetic modification

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3183

Platform:

GPL1261

4 Samples

Download data: CEL

(Submitter supplied) Human dermal lymphatic endothelial cells were cultured and treated with either vehicle or 10 nM AM for 15 minutes, 1 hour, or 24 hours to assess gene expression changes across the human genome with AM treatment.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4133

20 Samples

Download data: TXT

(Submitter supplied) In adults, there is a growing amount of data uncovering the cellular diversity of the pulmonary circulation and mechanisms governing vascular repair after injury, however, molecular and cellular mechanisms contributing to the morphogenesis and growth of the pulmonary vasculature during embryonic development are less clear. Importantly, deficits in vascular development lead to a large number of lung diseases in children, indicating a need to uncover fetal programs that promote pulmonary vascular growth. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

6 Samples

Download data: MTX, TSV