Similar studies for GEO DataSets (Select 3203) - GEO DataSets

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Items: 20

Select item 32031.

Analysis of monocytes following up to 168 hours of adherence-induced differentiation. Monocytes differentiate into macrophages, which are critical in the pathogenesis of many diseases. Results provide insight into the molecular mechanisms underlying monocyte to macrophage differentiation.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell type, 3 time sets

Platform:: GPL96
Series:: GSE8286
9 Samples

Download data: CEL

DataSet

Accession:: GDS3203

ID:: 3203

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000082862.

Gene expression profile during monocytes to macrophage differentiation

(Submitter supplied) Macrophages play a critical role in the pathogenesis of many diseases, including rheumatoid arthritis, inflammatory bowel disease and atherosclerosis. Monocytes recruited into tissues from peripheral blood differentiate into macrophages. There is limited data concerning the global changes in the expression of genes during monocyte to macrophage, and how the patterns of change identify the mechanism contributing to differentiation or macrophage function. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3203
Platform:: GPL96
9 Samples

Download data: CEL

Series

Accession:: GSE8286

ID:: 200008286

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000114083.

Expression Data From HCMV-Infected Human Monocytes Study 2

(Submitter supplied) Human cytomegalovirus induces a pro-inflammatory monocyte following infection. To begin to address how HCMV induces these rapid changes in infected monocytes, we examined the transcriptome of infected monocytes. Global transcriptional profiling using cDNA microarrays revealed a significant number of pro-inflammatory genes were upregulated within 4 hours post infection. Keywords: Disease State

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8300
12 Samples

Download data: CEL, CHP

Series

Accession:: GSE11408

ID:: 200011408

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000050994.

Expression Data from Macrophage Maturation and Polarization Experiment

(Submitter supplied) Monocytes were induced to mature to macrophages with M-CSF. Cells were then activated with Interferon gamma and LPS or IL-4.

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS2429 GDS2430
Platforms:: GPL97 GPL96
30 Samples

Download data: CEL

Series

Accession:: GSE5099

ID:: 200005099

Select item 24305.

Monocyte differentiation to macrophage and subsequent polarization (HG-U133B)

Analysis of monocytes (MCs) treated with M-CSF to induce differentiation into macrophages (MPs), and mature MPs treated with either IFN-gamma and LPS or IL-4 to induce polarization to M1 or M2 cells, respectively. Results provide insight into MC to MP differentiation and polarized activation.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 development stage sets

Platform:: GPL97
Series:: GSE5099
15 Samples

Download data: CEL

DataSet

Accession:: GDS2430

ID:: 2430

Select item 24296.

Monocyte differentiation to macrophage and subsequent polarization (HG-U133A)

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 development stage sets

Platform:: GPL96
Series:: GSE5099
15 Samples

Download data: CEL

DataSet

Accession:: GDS2429

ID:: 2429

Select item 2000373567.

Inflammatory Expression Profiles in Monocyte to Macrophage Differentiation amongst Patients with Systemic Lupus Erythematosus and Healthy Controls with and without an Atherosclerosis Phenotype

(Submitter supplied) To examine mononuclear cell gene expression profiles in patients with and without SLE and subsets with and without atherosclerosis

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
72 Samples

Download data: TXT

Series

Accession:: GSE37356

ID:: 200037356

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000244968.

Human Peripheral blood monocytes untreated or treated with CXCL12

(Submitter supplied) Total mRNA expression of CXCL12-treated monocytes was compared with control untreated monocytes

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL11010
6 Samples

Download data: TXT

Series

Accession:: GSE24496

ID:: 200024496

Select item 2000471229.

Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro

(Submitter supplied) To investigate the time-dependent and coordinated sequence of inflammation-related events, and the dynamic features of macrophage polarisation/activation, we build and validated an in vitro model based on primary human monocytes

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17180
60 Samples

Download data: CEL

Series

Accession:: GSE47122

ID:: 200047122

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001579110.

Homogeneous monocytes and macrophages from hES cells following coculture-free differentiation in M-CSF and IL-3.

(Submitter supplied) In the present study we aimed at producing homogeneous populations of monocytes and macrophages from human embryonic stem (hES) cells. Human embryonic stem cell lines KCL001, KCL002, and HUES-2 were differentiated into monocytes by coculture-free differentiation with two growth factors using a three-step method. The method involved embryoid body (EB) formation in hES media, directed differentiation with macrophage colony-stimulating factor and interleukin (IL)-3, and harvest of nonadherent monocytes from the culture supernatants. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
9 Samples

Download data: CEL

Series

Accession:: GSE15791

ID:: 200015791

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000963211.

Gene expression profiles of RAW264.7 macrophage cells treated with Paeony root-derived compounds

(Submitter supplied) Paeony root has long been used for its anti-inflammatory effects. In this study, the effects of albiflorin, paeoniflorin, and paeonol, compounds from paeony root, on gene expression profiles were examined in macrophages. The RAW264.7 macrophages were treated with LPS in the presence or absence of albiflorin, paeoniflorin, or paeonol. Global mRNA expression levels were detected by using an oligonucleotide microarray platform covering the mouse whole genome. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2995
33 Samples

Download data: TXT

Series

Accession:: GSE9632

ID:: 200009632

Select item 20000851512.

Identification of IL-1 and IL-6-responsive genes in human monocyte-derived macrophages

(Submitter supplied) Using whole-genome Affymetrix microarrays (HG-U133A), we characterized the transcriptome profile of cultured human macrophages stimulated for 4 h with interleukin 1 (IL-1) or interleukin 6 (IL-6). We found that, in distinction to liver cells, IL-1 is much more potent than IL-6 in modifying macrophage gene expression, although considerable heterogeneity in response of macrophages deriving from individual blood donors was observed. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3005
Platform:: GPL96
15 Samples

Download data: CEL

Series

Accession:: GSE8515

ID:: 200008515

Select item 300513.

Macrophage response to interleukins 1 and 6

Analysis of cultured monocyte-derived macrophages (MDM) stimulated with interleukin (IL) 1 or IL-6 for 4 hours. Cytokines IL-1 and IL-6 are not only produced by macrophages but also affect the cells in an autocrine manner. Results provide insight into IL-1 and IL-6 responsive genes in MDMs.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL96
Series:: GSE8515
15 Samples

Download data: CEL

DataSet

Accession:: GDS3005

ID:: 3005

Select item 20003451514.

Gene expression profiles of human blood classical monocytes (CD14++CD16-), CD16 positive monocytes (CD14+16++ and CD14++CD16+), and CD1c+ CD19- dendritic cells [human data]

(Submitter supplied) In this study gene expression of human blood classical monocytes (CD14++CD16-), CD16 positive monocytes (consisting of non-classical CD14+16++ and intermediate CD14++CD16+ monocytes) and CD1c+ CD19- dendritic cells from healthy subjects were investigated. Keywords: expression profiling by array

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
9 Samples

Download data: CEL, CHP

Series

Accession:: GSE34515

ID:: 200034515

Select item 20010354415.

Single-cell RNA-seq analysis of human CD14+ monocytes

(Submitter supplied) We performed single-cell RNA-seq on CD14+ monocytes isolated from the blood of healthy donors. Using the 10x chromium technology, we analyzed 425 and 431 cells from 2 individual donors.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
2 Samples

Download data: CSV

Series

Accession:: GSE103544

ID:: 200103544

PubMed Similar studies SRA Run Selector

Select item 20010204616.

Transcriptomic analysis of in vitro-generated human monocyte-derived cells

(Submitter supplied) We analyzed the transcriptomes of human dendritic cells and macrophages derived from monocytes using MCSF + IL-4 + TNFa, or IL-34 + IL-4 + TNFa, or dendritic cells derived from monocytes using GMCSF + IL-4.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL11532
30 Samples

Download data: CEL

Series

Accession:: GSE102046

ID:: 200102046

Select item 20006153517.

The transcriptome of Legionella pneumophila-infected human monocyte-derived macrophages

(Submitter supplied) Analysis of the human monocyte-derived macrophage (hMDM) transcriptional response to L. pneumophila infection at 8 hours post-infection We used microarrays to probe the hMDM transcriptional response to wild type L. pneumophila AA100 infection and its isogenic ankB and T2SS mutants. We identified up-regulation of innate immunity pathways and down-regulation of protein translation pathways

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
12 Samples

Download data: CEL

Series

Accession:: GSE61535

ID:: 200061535

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20006806118.

Human CD14+CD16- and CD16+ monocyte-derived macrophages primed by GM-CSF or M-CSF

(Submitter supplied) Identification of genes differentially expressed between human CD14+CD16- and CD16+ monocyte-derived macrophages generated in the presence of either GM-CSF (termed GM14 and GM16, respectively) or M-CSF (termed M14 and M16, respectively)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
12 Samples

Download data: TXT

Series

Accession:: GSE68061

ID:: 200068061

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20006896219.

Mesenchymal stromal cells perturb human monocyte in vitro differentiation into dendritic cells

(Submitter supplied) Monocytes cultured in media containing GM-CSF and IL4 for 5 days normally differentiate into immature dendritic cells which, upon further stimulation with LPS for an additional 2 days, acquire a mature phenotype. In the present study, we evaluated the effect of human cord-blood mesenchymal stem cells (MSC) on human monocyte differentiation into immature and mature DCs by examining the trancriptional profile of the cells that were obtained after both the differentiation and maturation stages.