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Links from GEO DataSets

Items: 5

1.
Full record GDS3415

Protocadherin 12 deficiency effect on the placenta

Analysis of embryonic day 12.5 placentas from animals lacking protocadherin 12 (Pcdh12). Pcdh12 is a transmembrane adhesive protein with homophilic adhesive properties. Pcdh12 deficient placentas exhibit a reduction in size. Results provide insight into the function of Pcdh12.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE7676
10 Samples
Download data: CEL, EXP
2.

Changes in gene expression following Protocadherin 12 knockout

(Submitter supplied) Protocadherin 12 (Pcdh12) is a transmembrane adhesive protein with homophilic adhesive properties and expressed in endothelial cells, the glycogen trophoblast cells of the placenta, and the mesangial cells of kidney glomeruli. Pcdh12-deficient mice are alive although they show alterations in placenta development. To reveal Pcdh12-associated pathways, 45,000 - Affymetrix probe arrays were used on Pcdh12 knockout and control placentas. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3415
Platform:
GPL1261
10 Samples
Download data: CEL, EXP
Series
Accession:
GSE7676
ID:
200007676
3.

Placental gene expression in severe preeclampsia.

(Submitter supplied) The series is composed of thirty hybridizations for analysis of differentially expressed genes in normal placenta tissues from patients with normal labor and placenta tissues from patients with severe preeclampsia. Patients tissues samples were obtained from (Vasilis. Total RNA extraction was performed by using the MagNa Pure Compact RNA Isolation Kit (Roche Applied Science). Keywords: Gene expression study, Disease state
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL2986
43 Samples
Download data: TXT
Series
Accession:
GSE10588
ID:
200010588
4.

Differential gene expression in placentae (E10.5) from adra2bKO and adra2bWT mice

(Submitter supplied) alpha2-adrenoceptors are essential presynaptic regulators of norepinephrine release from sympathetic nerves. Previous studies in mice with targeted deletions in the three alpha2-adrenoceptor genes have indicated that these receptors are essential for embryonic development. In the present study, we searched for the alpha2-adrenoceptor subtype(s) involved in placental development and its molecular mechanism using mice carrying targeted deletions in alpha2-adrenoceptor genes. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3108
Platform:
GPL1261
6 Samples
Download data: CEL
Series
Accession:
GSE6909
ID:
200006909
5.
Full record GDS3108

Alpha 2B-adrenoceptor deficient embryo and its placenta

Analysis of placentas of embryonic day E10.5 mutant embryos lacking alpha 2B-adrenoceptor (Adra2b). Adra2b-/- deficient embryos develop a defect in fetal and maternal vessel formation in the placenta labyrinth at E10.5. Results provide insight into the role of Adra2b in placental development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE6909
6 Samples
Download data: CEL
DataSet
Accession:
GDS3108
ID:
3108
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