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Links from GEO DataSets

Items: 4

1.
Full record GDS3507

Spinal cord injury effect on the urinary bladder: time course

Analysis of bladders from Sprague-Dawley females for up to 25 days following spinal cord injury (SCI). Bladder wall tissue compliance increases within 2 weeks after SCI in this animal model. Results provide insight into the molecular basis of the changes that the bladder undergoes after SCI.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 disease state, 4 time sets
Platform:
GPL85
Series:
GSE14096
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3507
ID:
3507
2.

Urinary bladder post-spinal cord injury: time-points

(Submitter supplied) Previously, we demonstrated using a rat model of spinal cord injury (SCI) that bladder wall tissue compliance significantly increased within the first 2 weeks following injury. In order to explore the potential molecular-level mechanisms of this event, the present study quantified molecules pertinent to bladder tissue remodeling and changes in mechanical properties. An initial gene array analysis followed by real-time qPCR revealed that the message levels for tropoelastin and lysyl oxidase were as high as 8-fold in SCI rats compared to normal. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3507
Platform:
GPL85
4 Samples
Download data: CEL, CHP
Series
Accession:
GSE14096
ID:
200014096
3.

Chronic contusion spinal cord injury in rats

(Submitter supplied) Excerpt from a larger study which characterized the transcriptional effects of a spinal cord contusion injury in rats. This is the data from the almost chronic contusion state (35 days) at the injury site (Thoracic 8) - where we saw significant changes in several areas, including cholesterol metabolism genes. Other spinal cord areas (rostral, caudal) and time-points (3 hours, 24 hours, 7 days and 35 days) were analyzed as well and are discussed in our paper and at www.crpf.org/microarray. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS1238
Platform:
GPL85
6 Samples
Download data
Series
Accession:
GSE2599
ID:
200002599
4.
Full record GDS1238

Spinal cord contusion

Expression profiling of contused spinal cords of Fischer animals. Spinal cords examined 35 days following contusion at the thoracic 8 segment. Results identify potential targets for therapeutic intervention following spinal cord injury.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 shock sets
Platform:
GPL85
Series:
GSE2599
6 Samples
Download data
DataSet
Accession:
GDS1238
ID:
1238
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