Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 20

1.
Full record GDS3824

Pineal gland development

Analysis of pineal gland across 5 developmental stages (3 larval, 2 adult) during the day and night. Pineal gland is a site of melatonin production, contains photoreceptor cells, and acts as a circadian clock pace maker. Results provide insight into the molecular basis of pineal gland development.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 5 age, 2 development stage, 2 time, 2 tissue sets
Platform:
GPL1319
Series:
GSE13371
69 Samples
Download data: CEL
2.

Transcriptome analysis of the zebrafish pineal gland

(Submitter supplied) The zebrafish pineal gland (epiphysis) is an autonomous clock organ. In addition to being a site of melatonin production, it contains photoreceptor cells and functions as a circadian clock pace maker, making zebrafish a useful model system to study the developmental control of expression of genes associated with melatonin synthesis and photodetection, and the circadian clock. Here we have used DNA microarray technology to study the zebrafish pineal transcriptome. more...
Organism:
Danio rerio
Type:
Expression profiling by array
Dataset:
GDS3824
Platform:
GPL1319
69 Samples
Download data: CEL
Series
Accession:
GSE13371
ID:
200013371
3.

Temporal expression data from zebrafish pineal gland

(Submitter supplied) Microarray data allowed detection of genes that have circadian expression pattern in the zebrafish pineal gland
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL1319
12 Samples
Download data: CEL
Series
Accession:
GSE41696
ID:
200041696
4.

Circadian Transcriptome of the Chicken Pineal In Vitro

(Submitter supplied) Chick pinealocytes exhibit all the characteristics of a complete circadian system, comprising photoreceptive inputs, molecular clockworks and an easily measured rhythmic output, melatonin biosynthesis. We used microarray analysis to investigate the expression of approximately 8000 genes within cultured pinealocytes subjected to both LD and DD cycles. We report that a reduced subset of genes were rhythmically expressed in vitro compared to those previously published in vivo, and that gene expression rhythms were lower in amplitude, although the functional distribution of the rhythmic transcriptome was largely similar. more...
Organism:
Gallus gallus
Type:
Expression profiling by array
Platform:
GPL3731
196 Samples
Download data
Series
Accession:
GSE5292
ID:
200005292
5.

Effect of light on gene expression in the zebrafish pineal gland

(Submitter supplied) Microarray data allowed detection of genes that are induced by light in the zebrafish pineal gland
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL1319
12 Samples
Download data: CEL
Series
Accession:
GSE53288
ID:
200053288
6.

Daily Rhythm in Expression of over 600 Genes in the Rodent Pineal Gland: Dominant Role of Adrenergic/cAMP Signaling

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platforms:
GPL1355 GPL85 GPL341
50 Samples
Download data: CEL
Series
Accession:
GSE12344
ID:
200012344
7.

Expt. C; Daily Rhythm in Expression of >600 Genes in the Rodent Pineal Gland: Dominant Role of Adrenergic/cAMP Signaling

(Submitter supplied) Biological processes are optimized by circadian and circannual biological timing systems. In vertebrates, the pineal gland plays an essential role in these systems by converting time into a hormonal signal, melatonin; in all vertebrates, circulating melatonin is elevated at night, independent of lifestyle. At night, sympathetic input to the pineal gland, originating from the circadian clock in the suprachiasmatic nucleus, releases norepinephrine. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Datasets:
GDS3701 GDS3702
Platform:
GPL1355
32 Samples
Download data: CEL
Series
Accession:
GSE12343
ID:
200012343
8.

Expt. B; Daily Rhythm in Expression of >600 Genes in the Rodent Pineal Gland: Dominant Role of Adrenergic/cAMP Signaling

(Submitter supplied) Biological processes are optimized by circadian and circannual biological timing systems. In vertebrates, the pineal gland plays an essential role in these systems by converting time into a hormonal signal, melatonin; in all vertebrates, circulating melatonin is elevated at night, independent of lifestyle. We have analyzed the rat pineal transcriptome at mid-day and mid-night to identify genes that exhibit night/day changes in expression. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3700
Platform:
GPL341
12 Samples
Download data: CEL
Series
Accession:
GSE12342
ID:
200012342
9.

Expt. A; Daily Rhythm in Expression of >600 Genes in the Rodent Pineal Gland: Dominant Role of Adrenergic/cAMP Signaling

(Submitter supplied) Biological processes are optimized by circadian and circannual biological timing systems. In vertebrates, the pineal gland plays an essential role in these systems by converting time into a hormonal signal, melatonin; in all vertebrates, circulating melatonin is elevated at night, independent of lifestyle. We have analyzed the rat pineal transcriptome at mid-day and mid-night to identify genes that exhibit night/day changes in expression. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3699
Platform:
GPL85
6 Samples
Download data: CEL
Series
Accession:
GSE12341
ID:
200012341
10.
Full record GDS3702

In vitro pineal gland organ culture response to adrenergic/cAMP stimulation (Expt. C)

Analysis of pineal organ cultures treated with norepinephrine (NE) and cAMP. Effects of forskolin also examined. Previous studies of night/day differentially expressed genes suggest control by NE/cAMP signaling. Results of this study expand the scope of the NE/cAMP regulatory cascade.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 4 agent sets
Platform:
GPL1355
Series:
GSE12343
12 Samples
Download data: CEL
11.
Full record GDS3701

Night and day effects on pineal gland and various other tissues (Expt. C)

Analysis of pineal glands and other tissues (retina, neocortex, cerebellum, hypothalamus, heart, and liver) obtained from Sprague-Dawley rats at mid-day (ZT7) or midnight (ZT19). Results provide insight into genes that characterize the pineal gland, independent of tonic or night/day influences.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 time, 7 tissue sets
Platform:
GPL1355
Series:
GSE12343
20 Samples
Download data: CEL
12.
Full record GDS3700

Night and day effects on pineal gland (Expt. B)

Analysis of pineal glands from Sprague-Dawley rats at mid-day (ZT7) or midnight (ZT19). Similar samples from pineal gland-specific DNF2 transgenic rats also examined. The pineal plays a vital role in vertebrate chronobiology. Results provide insight into night/day changes in pineal gene expression.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 time sets
Platform:
GPL341
Series:
GSE12342
12 Samples
Download data: CEL
13.
Full record GDS3699

Night and day effects on pineal gland (Expt. A)

Analysis of pineal glands from Sprague-Dawley rats at mid-day (Zeitgeber time ZT7) or midnight (ZT19). Rats were kept on a 14:10 light-dark (LD) cycle. The pineal gland plays a vital role in vertebrate chronobiology. Results provide insight into night/day changes in pineal gene expression.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 time sets
Platform:
GPL85
Series:
GSE12341
6 Samples
Download data: CEL
14.

RNA-sequencing project for zebrafish embryo and larva development

(Submitter supplied) Zebrafish is an important model system for the study of vertebrate embryonic development and adaptive immunese response. Recent years have seen great advancement in the understanding of the regulatory mechanisms during zebrafish embryogenesis and immune processes, yet large gaps still remain in the functional pathways critical for each developmental stage, especially for the late embryonic development. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL10658
9 Samples
Download data: TXT
Series
Accession:
GSE45706
ID:
200045706
15.

Identification of differentially expressed genes during development of the zebrafish pineal complex using RNA sequencing

(Submitter supplied) We describe a method for isolating RNA suitable for high-throughput RNA sequencing (RNA-seq) from small numbers of fluorescently labeled cells isolated from live zebrafish (Danio rerio) embryos without using costly, commercially available columns. This method ensures high cell viability after dissociation and suspension of cells and gives a very high yield of intact RNA. We demonstrate the utility of our new protocol by isolating RNA from fluorescence activated cell sorted (FAC sorted) pineal complex neurons in wild-type and tbx2b knockdown embryos at 24 hours post fertilization. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14875
8 Samples
Download data: TXT
Series
Accession:
GSE61202
ID:
200061202
16.

Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression

(Submitter supplied) The vertebrate pineal gland is dedicated to the production of the hormone melatonin, which increases at night to influence circadian and seasonal rhythms. This increase is associated with dramatic changes in the pineal transcriptome. Here, single-cell analysis of the rat pineal transcriptome was approached by sequencing mRNA from ~17,000 individual pineal cells, with the goals of profiling the cells that comprise the pineal gland and examining the proposal that there are two distinct populations of pinealocytes differentiated by the expression of Asmt, which encodes the enzyme that converts N-acetylserotonin to melatonin. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18694
10 Samples
Download data: GTF, MTX, TSV, TXT
Series
Accession:
GSE115723
ID:
200115723
17.

Expression data from zebrafish pineal gland

(Submitter supplied) Microarray data allowed detection of genes that are highly expressed in the pineal gland. Keywords: tissue expression pattern
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL1319
14 Samples
Download data: CEL
Series
Accession:
GSE13196
ID:
200013196
18.

Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20

(Submitter supplied) The cone-rod homeobox gene (Crx) encodes Crx, a transcription factor selectively expressed in two cell types, retinal photoreceptors and the melatonin secreting pinealocytes of the pineal gland. In this report the role of Crx in regulating gene expression in the mammalian pineal gland was extended using Affymetrix GeneChip technology. Deletion of Crx results in broad modulation of the mouse pineal transcriptome, including a >2-fold downregulation of 543 genes and a >2-fold upregulation of 745 genes. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
12 Samples
Download data: CEL, TXT
Series
Accession:
GSE24625
ID:
200024625
19.

RNA-Seq of the rat pineal transcriptome, with in-vivo and in-vitro samples, under various treatment and surgical conditions

(Submitter supplied) Pineal function follows a 24-hour schedule, dedicated to the conversion of night and day into a hormonal signal, melatonin. In mammals, 24-hour changes in pineal activity are controlled by a neural pathway that includes the central circadian oscillator in the suprachiasmatic nucleus and the superior cervical ganglia (SCG), which innervate the pineal gland. In this study, we have generated the first next-generation RNA sequencing evidence of neural control of the daily changes in the pineal transcriptome. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14844
36 Samples
Download data: TXT, XLSX
Series
Accession:
GSE63309
ID:
200063309
20.

Pineal gland gene expression of 129 Wt P0 mice versus NeuroD1 pineal gene expression at P0

(Submitter supplied) This study determines pineal gland gene expression levels in the NeuroD1 knockout mouse at postnatal day zero. Comparison was performed against pineal gland gene expression levels in 129 wildtype mice also disected at P0. Keywords: Comparison of wildtype versus transgenic pineal gland gene expression
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3000
Platform:
GPL1261
6 Samples
Download data: CEL
Series
Accession:
GSE6030
ID:
200006030
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=5|blobid=MCID_614936782a02ec76334581e2|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center