GEO DataSets

Analysis of highly localized regions of salivary gland epithelia from 12.5-, 13.5-, 14-, and 15-day-old ICR embryos. Development of mouse submandibular salivary gland begins at E11.5. Results provide insight into molecular mechanisms underlying salivary gland development and differentiation.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 4 age, 6 tissue sets

Platform:

GPL7202

Series:

GSE22828

84 Samples

Download data: TXT

(Submitter supplied) The goal of this study was to generate a spatiotemporal atlas of gene expression in the developing salivary gland. This will allow us to identify changes in gene expression that may result in the formation of the different domains of the salivary gland.

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3922

Platform:

GPL7202

84 Samples

Download data: TIFF, TXT, XLS, XLSX

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL18480 GPL19057

19 Samples

Download data: MTX, TSV

(Submitter supplied) Our single-cell and bulk transcriptome analyses revealed striking molecular heterogeneity in the mesenchymal cells of embryonic submandibular and parotid salivary glands during bud initiation, including distinct mesodermal and neural crest-derived molecular signatures that foreshadow later functions.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19057

4 Samples

Download data: MTX, TSV

(Submitter supplied) Our single-cell and bulk transcriptome analyses revealed striking molecular heterogeneity in the mesenchymal cells of embryonic submandibular and parotid salivary glands during bud initiation, including distinct mesodermal and neural crest-derived molecular signatures that foreshadow later functions.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18480

15 Samples

Download data: TXT

(Submitter supplied) Mus musculus embryonic submandibular salivary glands from embryonic day 12.5 embryos were laser microdissected to isolate epithelial cells from regions adjacent to forming clefts or from the peripheral end bud region. The isolated region-specific samples were then subjected to T7-SAGE transcriptome analysis.

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL11

2 Samples

Download data

(Submitter supplied) In order to elucidate the relationship between CXC chemokine receptor 4 (CXCR4) and embryonic organogenesis, we performed 3' mRNA-seq on control and AMD3100-treated eSMGs.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19057

6 Samples

Download data: TXT

(Submitter supplied) To investigate the roles of YAP in the submandibular gland (SMG) epithelium, we compared the gene expression profiles of E15.5 SMGs isolated from Yap-loxP/loxP or Yap-loxP/loxP;Shh-Cre (i.e. Cre recombinase from the Shh promoter) embryos.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL22412

6 Samples

Download data: CEL

(Submitter supplied) Analysis of gene expression changes during mouse salivary gland development using RNA-Seq

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

13 Samples

Download data: CSV

(Submitter supplied) RON WT and RON KO at 5, 6, 7 week virgin mammary glands In the study, we demonstrated that RON regulates mammary gland branching morphogenesis in pubertal development associated with changes in gene expression. Keywords: Pubertal mammary glands

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

18 Samples

Download data: CEL

(Submitter supplied) Transcription factors drive organogenesis, from the initiation of cell fate decisions to the maintenance and implementation of these decisions. The Drosophila embryonic salivary gland provides an excellent platform for unraveling the underlying transcriptional networks of organ development because Drosophila is relatively unencumbered by significant genetic redundancy. The highly conserved FoxA family transcription factors are essential for various aspects of organogenesis in all animals that have been studied. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

6 Samples

Download data: CEL

(Submitter supplied) Development of branching organs involves a series of events regulated by proliferation, differentiation, and intricate cell-cell communication networks. Understanding the molecular drivers for these developmental stages is instrumental to device effective regenerative therapies. Here, we use single cell RNAseq of murine submandibular gland (SMG) from developmental stages corresponding to end bud initiation (E12), branching morphogenesis (E14), cytodifferentiation (E16) and postnatal development (P1, P30, and adult) to generate an atlas of SMG development. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19057

7 Samples

Download data: H5, MTX, TSV