Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 15

1.
Full record GDS3930

Bone morphogenic protein effect on cultured sympathetic neurons: time course

Analysis of superior cervical ganglia (SCG) cultured neurons treated with bone morphogenic protein-7 (BMP-7) for 6 or 24h. Addition of BMPs triggers these neurons to extend multiple dendrites. Results provide insight into molecular mechanisms underlying initial formation of primary dendrites.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent, 2 time sets
Platform:
GPL85
Series:
GSE28150
9 Samples
Download data: CEL
2.

Transcriptional responses of sympathetic neurons during BMP-induced primary dendritogenesis

(Submitter supplied) The objective of this study was to identify genes that are differentially regulated in cultured sympathetic neurons during BMP-induced dendritic growth and to determine the temporal expression patterns of these genes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3930
Platform:
GPL85
9 Samples
Download data: CEL
Series
Accession:
GSE28150
ID:
200028150
3.

MicroRNAs are important mediators of BMP-7 induced dendritic growth in sympathetic neurons

(Submitter supplied) MicroRNA profiling of cultured sympathetic neurons from the superior cervical ganglia of E21 Sprague-Dawley rat pups following growth under control conditions or after treatment with BMP-7 at 50 ng/mL for 6 hours or 24 hours.
Organism:
Rattus norvegicus
Type:
Non-coding RNA profiling by array
Platform:
GPL20108
6 Samples
Download data: TXT, XLS
Series
Accession:
GSE123746
ID:
200123746
4.

Microarray gene expression profiling of isolated class I and class IV Drosophila dendritic arborization sensory neurons

(Submitter supplied) Class I and IV Drosophila dendritic arborization sensory neurons were isolated via magnetic bead sorting and total RNA isolated from the samples was used for gene expression profiling. Elucidating the molecular mechanisms controlling dendrite development is key to understanding the pivotal role these structures play in influencing synaptic integration and neural function. Despite significant advances in this field, genetic pleiotropy remains a significant impediment to investigating such complex developmental processes. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL7300
7 Samples
Download data: TXT
Series
Accession:
GSE46154
ID:
200046154
5.

Transcriptional Profiling of Class IV da Neurons

(Submitter supplied) Elucidating the molecular mechanisms controlling dendrite development is key to understanding the pivotal role these structures play in influencing synaptic integration and neural function. Despite significant advances in this field, genetic pleiotropy remains a significant impediment to investigating such complex developmental processes. To circumvent this problem, we have applied class specific neuron transcriptional expression profiling coupled to an in vivo RNAi functional validation screen in order to dissect the molecular bases of Drosophila class IV dendritic arborization (da) neuron dendritogenesis. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL6385
2 Samples
Download data: TXT
Series
Accession:
GSE28675
ID:
200028675
6.

Patterns of gene expression following contact of sympathetic neurons with their myocyte targets

(Submitter supplied) We identified 112 known genes and 150 expressed sequence tags (ESTs) showing more than a 1.3 fold change in target-exposed neurons compared to neurons grown in the absence of target. Expression of 36 genes and 49 ESTs was upregulated, while expression of 76 genes and 101 ESTs was downregulated by the presence of target during the culture period. Overall, these changes represented approximately 1.6% of the probe set. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL341
2 Samples
Download data: CEL
Series
Accession:
GSE8393
ID:
200008393
7.

Gene expression analysis of SCG sympathetic neurons with loss of Egr3

(Submitter supplied) The transcription factor Egr3 has been shown to have a cell autonomous role in sympathetic nervous system (SNS) development. We utilized microarray analysis to identify potential downstream target genes deregulated with loss of Egr3. Both conditions were in the null Bax background to prevent apoptosis and therefore mitigate identification of apoptosis related genes. Our analysis identified genes involved in biological processes that were expected such as SNS development and axonogenesis as well as those that were unexpected such as dendritogenesis and axon guidance. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6105
6 Samples
Download data: TXT
Series
Accession:
GSE41290
ID:
200041290
8.

Comparative gene expression profile of Ngn3-overexpressing cultured hippocampal neurons vs the corresponding control populations

(Submitter supplied) Gene expression profiles of Ngn3-overexpressing cultured hippocampal neurons was compared to the profile of the corresponding control populations. (neurons expressing GFP). Neurogenin3, a proneural transcription factor controlled by Notch receptor, is involved in hippocampal neuron differentiation and synapses, but little is known about the molecular bases of Ngn3 activity in neurons. Microarray analysis indicated that overexpression of Ngn3 upregulated a number of genes related with cytoskeleton dynamics. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL8063
8 Samples
Download data: TXT
Series
Accession:
GSE26911
ID:
200026911
9.

Human breast cancer cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
60 Samples
Download data: TXT
Series
Accession:
GSE31605
ID:
200031605
10.

Human breast cancer cell lines: vehicle vs. BMP7 incubation

(Submitter supplied) Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily of growth factors. They are known for their roles in regulation of osteogenesis and developmental processes and, in recent years, evidence has accumulated of their crucial functions in tumor biology. BMP7, in particular, has been implicated in breast cancer. However, little is known about BMP target genes in the context of tumor. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
30 Samples
Download data: TXT
Series
Accession:
GSE31604
ID:
200031604
11.

Human breast cancer cell lines: vehicle vs. BMP4 incubation

(Submitter supplied) Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily of growth factors. They are known for their roles in regulation of osteogenesis and developmental processes and, in recent years, evidence has accumulated of their crucial functions in tumor biology. BMP4, in particular, has been implicated in breast cancer. However, little is known about BMP target genes in the context of tumor. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
30 Samples
Download data: TXT
Series
Accession:
GSE31603
ID:
200031603
12.

Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells

(Submitter supplied) Analysis of BMP-2 induced gene expression of C2C12 cells treated with the endocytosis inhibitor dynasore to identify gene expression profiles which are sensitive to endocytosis inhibition. Our data highlight the importance of endocytosis for transmission of an extracellular BMP-2 signal into the nucleus to activate a transcriptional gene network
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
8 Samples
Download data: TXT
Series
Accession:
GSE29373
ID:
200029373
13.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3643
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE10748
ID:
200010748
14.
Full record GDS3643

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 6 dose sets
Platform:
GPL1355
Series:
GSE10748
24 Samples
Download data: CEL
DataSet
Accession:
GDS3643
ID:
3643
15.

Modular transcriptional programs separately define axon and dendrite connectivity

(Submitter supplied) Patterns of synaptic connectivity are remarkably precise and complex. Single-cell RNA sequencing has revealed a vast transcriptional diversity of neurons. Nevertheless, a clear logic underlying the transcriptional control of neuronal connectivity has yet to emerge. Here, we focused on Drosophila T4/T5 neurons, a class of closely related neuronal subtypes with different wiring patterns. Eight subtypes of T4/T5 neurons are defined by combinations of two patterns of dendritic inputs and four patterns of axonal outputs. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21306
2 Samples
Download data: MTX, TSV, TXT
Series
Accession:
GSE126139
ID:
200126139
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=5|blobid=MCID_6173e9e38137be714a20867e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center