GEO DataSets

Analysis of lung from ICR females over a time course beginning at embryonic day 12 and continuing into adulthood, encompassing all recognized stages of lung development. These results, together with miRNA profiling results, provide insight into molecular mechanisms underlying lung organogenesis.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 7 age sets

Platform:

GPL1261

Series:

GSE21053

14 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array; Other; Non-coding RNA profiling by array

Dataset:

GDS3950

Platforms:

GPL1261 GPL10253

28 Samples

Download data: CEL, TXT

(Submitter supplied) We performed miRNA and mRNA profiling over a 7-point time course, encompassing all recognized stages of lung development and explore dynamically regulated miRNAs and potential miRNA-mRNA interaction networks specific to mouse lung development

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array; Other

Platform:

GPL10253

14 Samples

Download data: TXT

(Submitter supplied) We performed miRNA and mRNA profiling over a 7-point time course, encompassing all recognized stages of lung development and explore dynamically regulated miRNAs and potential miRNA-mRNA interaction networks specific to mouse lung development

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

14 Samples

Download data: CEL

(Submitter supplied) BACKGROUND: Development of the neural tube is a highly orchestrated process relying on precise, spatio-temporal expression of numerous genes as well as hierarchies of signal transduction and gene regulatory networks. Disruption of expression of a number of genes participating in these networks is believed to underlie developmental anomalies such as neural tube defects (NTDs) resulting from anomalous neural tube morphogenesis. more...

Organism:

Mus musculus; Rattus norvegicus; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL10178

9 Samples

Download data: TXT

(Submitter supplied) We sequenced mammary gland samples of MMTV-PyMT mouse from 4 stages (hyperplasia at week 6, adenoma/MIN at week 8, early carcinoma at week 10, and late carcinoma with lung metastasis at week 12) during tumor progression.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL17021

24 Samples

Download data: CSV

(Submitter supplied) MicroRNAs (miRNAs) are small regulatory molecules that cause post-transcriptional gene silencing. Although some miRNAs are known to have region-specific expression patterns in the adult brain, the functional consequences of the region-specificity to the gene regulatory networks of the brain nuclei are not clear. Therefore, we studied miRNA expression patterns by miRNA-seq in two brain regions, frontal cortex (FCx) and hippocampus (HP), which have separate biological functions. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL9250

12 Samples

Download data: BED, TXT

(Submitter supplied) We used Affymetrix miRNA arrays to analyze the expression of miRNAs in the frontal cortex and hippocampus of 8-week-old C57BL/6J wt mice. We compared these microarray-based expression profiles to ones obtained by miRNA sequencing from the same brain regions of the same mouse strain.

Organism:

synthetic construct; Mus musculus

Type:

Expression profiling by array

Platform:

GPL8786

6 Samples

Download data: CEL

(Submitter supplied) qPCR profiling of miRNAs in mouse fetal lungs was done. Lungs were dissected and RNA was extracted using miRVANA extraction kit (Applied Biosystems).

Organism:

Mus musculus

Type:

Expression profiling by RT-PCR

Platform:

GPL17017

32 Samples

Download data: TXT

(Submitter supplied) miRNA played an important role in the process of carcinogenesis in HBV related hepatocellular carcinoma. Therefore, we performed miRNA microarray to evaluate the miRNAs that expressed differentially between HCC tumor versus non-tumor liver tissues.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL10850

10 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array; Expression profiling by RT-PCR

Platforms:

GPL11199 GPL1261

20 Samples

Download data: CEL, SDS

(Submitter supplied) We performed miRNA and mRNA profiling at postnatal day 14 and day 29 to compare hyperoxia-induced bronchopulmonary dysplasia and wild type. We built potential miRNA-mRNA interaction networks specific to brochopulmonary dysplasia.

Organism:

Mus musculus

Type:

Expression profiling by RT-PCR

Platform:

GPL11199

10 Samples

Download data: SDS

(Submitter supplied) We performed miRNA and mRNA profiling at postnatal day 14 and day 29 to compare hyperoxia-induced bronchopulmonary dysplasia and wild type. We built potential miRNA-mRNA interaction networks specific to brochopulmonary dysplasia.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

10 Samples

Download data: CEL

(Submitter supplied) The regulation of gene expression in cells, including by microRNAs (miRNAs), is a dynamic process. Current methods for identifying microRNA targets by combining sequence, miRNA and mRNA expression data do not adequately utilize the temporal information and thus miss important miRNAs and their targets. We developed a new method, mirDREM, that uses probabilistic modeling to reconstruct dynamic regulatory networks which explain how temporal gene expression is jointly regulated by microRNAs and transcription factors (TFs). more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL10787

40 Samples

Download data: TXT

(Submitter supplied) Microarray data of mouse postnatal lungs between day 1 and 6 weeks of age. The results provide a general insight into the gene expression profile during the alveolar phase of lung development.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL10787

24 Samples

Download data: TXT

(Submitter supplied) Vehicle versus Doxycycline miRNA induction.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL24247 GPL21103

10 Samples

Download data: TAB, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array; Other

Platforms:

GPL1261 GPL11199

8 Samples

Download data: CEL

(Submitter supplied) We performed miRNA and mRNA profiling in BASC cells and c-Myc depleted BASC cells. We built potential miRNA-mRNA interaction networks specific to c-Myc regulation in BASCs

Organism:

Mus musculus

Type:

Other

Platform:

GPL11199

4 Samples

Download data: TXT

(Submitter supplied) We performed miRNA and mRNA profiling in BASC cells and c-Myc depleted BASC cells. We built potential miRNA-mRNA interaction networks specific to c-Myc regulation in BASCs

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

4 Samples

Download data: CEL

(Submitter supplied) Analysis of early stages of alcohol dependence at the gene expression level. The hypothesis tested in the present study was that ethanol-treatment impact gene expression in a mouse model of high ethanol consumption. Results provide important information of genes and pathways being affected by ethanol actions in the mouse frontal cortex.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6885

32 Samples

Download data: TXT