GEO DataSets

Analysis of lymphoid cell lines of Hodgkin, non-Hodgkin, and acute leukemia origin. Aberrant NOTCH activity is involved in the pathogenesis of B cell-derived lymphomas. Results provide insight into the molecular basis of deregulated NOTCH activity.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 9 cell line, 4 disease state sets

Platform:

GPL570

Series:

GSE20011

15 Samples

Download data: CEL

(Submitter supplied) Genomewide gene expression analysis of lymphoid cell lines of Hodgkin, non-Hodgkin and acute leukemia origin

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4179

Platform:

GPL570

15 Samples

Download data: CEL

(Submitter supplied) NOTCH/RBPJ/MAML ternary transcriptional complex binds to regulatory element and drives gene expression. The complex can function as monomer and dimer. How dimeric complexes regulate gene expression in human cancer is not well studied. Here, we integrate genomic data sets and analyze Notch dimeric complexes-regulated transcriptome and cis-regulatory elements. A subset of coding and non-coding RNA is Notch dimeric complexes-associated. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL11154

16 Samples

Download data: TXT

(Submitter supplied) NOTCH/RBPJ/MAML ternary transcriptional complex binds to regulatory element and drives gene expression. The complex can function as monomer and dimer. How dimeric complexes regulate gene expression in human cancer is not well studied. Here, we integrate genomic data sets and analyze Notch dimeric complexes-regulated transcriptome and cis-regulatory elements. A subset of coding and non-coding RNA is Notch dimeric complexes-associated. more...

Organism:

Homo sapiens

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL11154

4 Samples

Download data: BW