Similar studies for GEO DataSets (Select 4418) - GEO DataSets

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Items: 17

Select item 44181.

Analysis of bronchial biopsies from allergic asthma (AA) subjects. These results, together with those from GDS4417 (a study with similar specimen collection procedures, but different subjects, GeneChips, data processing), provide insight into molecular mechanisms underlying AA pathophysiology.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL96
Series:: GSE41649
8 Samples

Download data: CEL

DataSet

Accession:: GDS4418

ID:: 4418

Select item 2000416492.

Comparison of two sets of microarray experiments to define allergic asthma expression pattern

(Submitter supplied) Allergic asthma is a complex trait. Several approaches have been used to identify biomarkers involved in this disease. This study aimed at demonstrating the relevance and validity of microarrays in the definition of allergic asthma expression pattern. The authors compared the transcript expressions of bronchial biopsy of 2 different microarray experiments done 2 years apart, both including nonallergic healthy and allergic asthmatic subjects (n = 4 in each experiment). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4418
Platform:: GPL96
8 Samples

Download data: CEL

Series

Accession:: GSE41649

ID:: 200041649

Select item 2000341723.

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
34 Samples

Download data: CEL

Series

Accession:: GSE34172

ID:: 200034172

Select item 2000341604.

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR and EDTA)

(Submitter supplied) To determine differential gene expression in peripheral blood of asthmatic individuals undergoing allergen inhalation challenge, post-challenge compared to pre-challenge

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
18 Samples

Download data: CEL

Series

Accession:: GSE34160

ID:: 200034160

Select item 2000341595.

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR)

(Submitter supplied) Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using non-globin reduced PAXgene (PAX.NGR) tubes Blood was collected immediately prior to, and two hours after challenge

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
8 Samples

Download data: CEL

Series

Accession:: GSE34159

ID:: 200034159

Select item 2000341586.

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.GR)

(Submitter supplied) Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using globin reduced PAXgene (PAX.GR) tubes

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
8 Samples

Download data: CEL

Series

Accession:: GSE34158

ID:: 200034158

Select item 2000158237.

Functional classes of bronchial mucosa genes that are differentially expressed in asthma

(Submitter supplied) Asthma pathogenesis and susceptibility involves a complex interplay between genetic and environmental factors. We report the results of expression microarray studies using tissue obtained from bronchial biopsies of healthy controls and of subjects with allergic asthma, both before and following inhaled corticotherapy.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4417
Platform:: GPL8300
12 Samples

Download data: CEL

Series

Accession:: GSE15823

ID:: 200015823

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 44178.

Inhaled corticotherapy effect on allergic asthma: bronchial biopsies

Analysis of bronchial biopsies from allergic asthma (AA) subjects following inhaled corticosteroids (ICS) therapy. ICS represent potent anti-inflammatory controller medications for the treatment of asthma. Results provide insight into molecular mechanisms underlying the pathophysiology of AA.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent, 2 disease state, 2 specimen sets

Platform:: GPL8300
Series:: GSE15823
12 Samples

Download data: CEL

DataSet

Accession:: GDS4417

ID:: 4417

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000225289.

Gene expression pattern of alveolar macrophages of allergic asthmatics in comparison with control subjects

(Submitter supplied) The implication of alveolar macrophages (AM) in asthma, a Th2 disease, has not been well characterized. Thus, the goal of this study is to better characterize AM phenotype of allergic asthmatic compared with normal subjects using genomic expression analyses. Microarray analyses were performed with AM isolated from bronchoalveolar lavage. Robust multiarray analysis (RMA) normalization and Smyth’s moderated t test were used to select differentially expressed genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5245
Platform:: GPL96
10 Samples

Download data: CEL

Series

Accession:: GSE22528

ID:: 200022528

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 524510.

Allergic asthma: alveolar macrophage

Comparison of alvelolar macrophages (AMs) of allergic asthma (AA) patients and healthy subjects. AMs are the main immune cells in the airway lumen and are in direct contact with exogenous agents. Results provide insight into the differences between the AMs of AA patients and healthy individuals.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL96
Series:: GSE22528
10 Samples

Download data: CEL

DataSet

Accession:: GDS5245

ID:: 5245

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20003899411.

Next-Generation Transcriptome Sequencing (RNA-Seq) of Human Endobronchial Biopsies: Asthma vs Controls

(Submitter supplied) Rationale: The cellular and molecular pathways in asthma are highly complex. Increased understanding can be obtained by unbiased transcriptomic analysis (RNA-Seq). Hypothesis and Aims: We hypothesized that the transcriptomic profile of whole human endobronchial biopsies differs between patients with asthma and controls. First, we investigated the feasibility to obtain RNA from whole endobronchial biopsies suitable for RNA-Seq. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL14603
2 Samples

Download data: CSV

Series

Accession:: GSE38994

ID:: 200038994

PubMed Similar studies SRA Run Selector

Select item 20000430212.

Genome-Wide Profiling of Airway Epithelial Cells in Asthmatics, Smokers and Healthy Controls

(Submitter supplied) We collected airway epithelial brushings for microarray analysis from 42 asthmatics and two control groups – 28 healthy subjects and 16 smokers. A subgroup of 32 asthmatics completed a randomized placebo-controlled trial of fluticasone propionate in which collection of brushings was repeated after 1 week of treatment. Keywords: disease state analysis, clinical trial

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
118 Samples

Download data: CEL

Series

Accession:: GSE4302

ID:: 200004302

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005460513.

The relationship between expression imbalance of adhesion molecules and asthma pathogenesis

(Submitter supplied) Accumulated research has suggested the importance of the adhesion molecules modulation as therapeutic approach for bronchial asthma. Adhesion molecules expression alteration contributes to the pathogenesis of asthma. In order to probe the relationship between expression imbalance of adhesion molecules and asthma pathogenesis, expression profiling of adhesion molecules was performed using cDNA microarray. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1162
10 Samples

Download data: TXT

Series

Accession:: GSE54605

ID:: 200054605

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000601214.

Skin biopsies from atopic eczema and healthy controls

(Submitter supplied) The aim of this study was to find disease-associated genes in atopic eczema. Keywords: Skin biopsy, DNA microarray, atopic eczema

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
20 Samples

Download data

Series

Accession:: GSE6012

ID:: 200006012

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000047315.

PGA Human CD4+ Lymphocytes

(Submitter supplied) This project is based on the hygiene hypothesis that exposure to TB provides a protective mechanism against asthma through specific cytokines and the balance of Th1, Th2 cells. Additionally, expression changes are examined in patients with and without atopy in combination with asthma and PPD status. Expression levels were evaluated in CD4+ cells isolated from peripheral blood of 30 patients. Each patient was evaluated on the entire U133 Affymetrix GeneChip set. more...