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Links from GEO DataSets

Items: 3

1.
Full record GDS5278

Endometrium response to tamoxifen and low dose estradiol combination therapy

Analysis of endometria of postmenopausal cynomolgus macaques treated with tamoxifen and low dose estradiol. Tamoxifen is a selective estrogen receptor modulator (SERM). Estrogen and SERM co-therapy is an alternative to estrogen and progestin, a treatment associated with increased breast cancer risk.
Organism:
Macaca fascicularis; Macaca mulatta
Type:
Expression profiling by array, count, 4 agent sets
Platform:
GPL3535
Series:
GSE14518
16 Samples
Download data: CEL, CHP
2.

Endometrial profile of low-dose estradiol and tamoxifen combination therapy

(Submitter supplied) Combination therapy with estrogen and a selective estrogen receptor modulator (SERM) is a promising approach to safely alleviate important side effects related to estrogen deficiency in women at high risk for breast cancer. Data related to endometrial safety of estrogen+SERM co-therapies are limited, however. The primary goal of this study was to evaluate the endometrial profile of low-dose E2 and Tam alone and in combination.
Organism:
Macaca fascicularis; Macaca mulatta
Type:
Expression profiling by array
Dataset:
GDS5278
Platform:
GPL3535
16 Samples
Download data: CEL, CHP
Series
Accession:
GSE14518
ID:
200014518
3.

mRNA expression data from mice infected with H. pylori treated with estradiol, tamoxifen, or placebo

(Submitter supplied) We are investigating the mRNA expression profiles of gastric tissue within H. pylori-infected mice treated with estradiol, tamoxifen, or placebo We used microarrays to compare the global mRNA expression profiles in H. pylori infected mice in response to estradiol and tamoxifen
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL7202
8 Samples
Download data: TXT
Series
Accession:
GSE29715
ID:
200029715
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