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Items: 4

1.
Full record GDS5464

NFATc1 deficiency effect on osteoclast differentiation in vitro

Analysis of osteoclasts lacking the transcription factor NFATc1. Osteoclasts cultured in the presence of M-CSF and RANKL to induce differentiation. Results identify gene targets of NFATc1 in osteoclastogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL8321
Series:
GSE37219
4 Samples
Download data: CEL
2.

Comparison expression data from wild-type and NFATc1-deficient osteoclasts

(Submitter supplied) Genetic deletion of Nfatc1 in mice results in profound osteoclast-poor osteopetrosis, a high bone mass state caused by a lack of osteoclast activity. We hypothesized that the family of NFATc1 regulated transcripts in the osteoclast would be enriched for genes associated with osteoclast function. We used microarrays profile gene expression in wild-type and NFATc1-deficient osteoclasts generated in vitro to identify NFATc1-dependent transcripts in osteoclasts.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5464
Platform:
GPL8321
4 Samples
Download data: CEL
Series
Accession:
GSE37219
ID:
200037219
3.

Microarray analysis of Macrophages and Osteoclasts

(Submitter supplied) Comparaison of genes expression between bone marrow derived macrophages and osteoclasts in C57BL/6J mice
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
2 Samples
Download data: TXT
Series
Accession:
GSE86998
ID:
200086998
4.

Ethyl acetate fraction of Lentinula edodes (LEA) inhibits osteoclastogenesis by suppressing NFATc1 expression

(Submitter supplied) To screen for altered gene expression during osteoclastogenesis, BMM cells treated with RANKL or RANKL+LEA were subjected to gene expression profiling.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
6 Samples
Download data: XLSX
Series
Accession:
GSE142866
ID:
200142866
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