Format
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 3

1.
Full record GDS5800

Interstitial fluid flow effect on noninvasive and invasive ERBB2-positive breast cancer cells

Analysis of non-invasive NeuN cells and invasive NeuT cells (i.e., MCF10A cells overexpressing wild-type ERBB2 or a constitutively active mutant of ERBB2, respectively) treated with IFF. Results provide insight into the molecular pathways activated by IFF in ERBB2-positive breast cancer cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 cell line, 2 protocol sets
Platform:
GPL10558
Series:
GSE64670
12 Samples
Download data
DataSet
Accession:
GDS5800
ID:
5800
2.

EMT Alters Interstitial Fluid Flow-induced Signaling in ERBB2-positive Breast Cancer

(Submitter supplied) A variety of mechanotransduction forces are altered in the tumor microenvironment (TME) and these biophysical forces can influence cancer progression. One such force is interstitial fluid flow (IFF) - the movement of fluid through the tissue matrix. IFF was previously shown to induce invasion of cancer cells, but the activated signaling cascades remain poorly understood. Here, it is demonstrated that IFF induces invasion of ERBB2/HER2 expressing breast cancer cells via activation of phosphoinositide-3-kinase (PI3K). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5800
Platform:
GPL10558
12 Samples
Download data: TXT
Series
Accession:
GSE64670
ID:
200064670
3.

Expression data from H358

(Submitter supplied) Tumors that show evidence of epithelial to mesenchymal transition (EMT) have been associated with metastasis, drug resistance, and poor prognosis. EMT may alter the molecular requirements for growth and survival in different contexts, but the underlying mechanisms remain incomplete. Given the heterogeneity along the EMT spectrum between and within tumors it is important to define the requirements for growth and survival in cells with an epithelial or mesenchymal phenotype to maximize therapeutic efficacy. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE52308
ID:
200052308
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=2|blobid=MCID_61edc8986649947d0726075d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center