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Items: 20

1.
Full record GDS583

Aging time course, normal adult

Examination of normal adult aging using synchronized populations at 0 - 144 hours. Employed CF512 fer-15(b26) II; fem-1 (hc17) IV mutant strain, which has defective spermatids thus eliminating contributions from embryonic transcripts.
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array, log ratio, 7 age sets
Platform:
GPL576
Series:
GSE832
7 Samples
Download data
DataSet
Accession:
GDS583
ID:
583
2.

C. elegans heat stress time course

(Submitter supplied) We sought to study the effect of heat stress on gene expression in C. elegans. We cultured CF512 animals to adulthood at 25C (at which they are sterile). We then induced heat stress by switching the culture temperature to 30C. Keywords: time-course
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array
Dataset:
GDS584
Platform:
GPL924
7 Samples
Download data
Series
Accession:
GSE946
ID:
200000946
3.

Adult aging in C. elegans

(Submitter supplied) We wished to study normal adult aging in C. elegans. We competitively hybridized a series of experimental samples (experimental variable: adult age) against a common reference sample. We use the CF512 fer-15(b26) II; fem-1 (hc17) IV mutant strain, which has defective spermatids which fail to activate into spermatozoa at 25C. Culturing this strain at 25C prevented self-fertilization and therefore eliminated contributions from embryonic transcripts. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array
Dataset:
GDS583
Platform:
GPL576
7 Samples
Download data
Series
Accession:
GSE832
ID:
200000832
4.

Oxidative stess in Drosophila heads

(Submitter supplied) Profiled the effect of oxidative stress on gene expression in the heads of adult Drosophila. The flies were fed sucrose with 15mM paraquat (experimental condition) or regular sucrose (control condition) for 30 hours, before harvesting at adult d3. Keywords = oxidative stress Keywords = paraquat Keywords: dose response
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL72
2 Samples
Download data
Series
Accession:
GSE827
ID:
200000827
5.

Aging in heads from adult Drosophila males, w118 strain

(Submitter supplied) The w1118 strain is an inbred lab stock widely used in genetic and transgenic studies. w1118 males have a median life span of 35 days. Adult males were collected within 24 hr after eclosion. Approximately 200 flies were maintained in constant darkness in each food bottle at 25°C and 70% humidity and were transferred to fresh bottles every 3-4 days. Transcripts were harvested at d3 and d47. To separate the head from the rest of the body, flies were frozen and briefly vortexed in liquid nitrogen. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL72
2 Samples
Download data
Series
Accession:
GSE826
ID:
200000826
6.
Full record GDS584

Heat stress time course

Examination of effect of heat stress. Adult CF512 cultured at 25°C, then switched to 30°C and sampled over 12 hour time period.
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array, log ratio, 7 time sets
Platform:
GPL924
Series:
GSE946
7 Samples
Download data
DataSet
Accession:
GDS584
ID:
584
7.

Evolution of gene expression in the Drosophila melanogaster subgroup update and extension

(Submitter supplied) http://0-www.nature.com.brum.beds.ac.uk/ng/journal/v33/n2/abs/ng1086.html. Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition?the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...
Organism:
Drosophila simulans; Drosophila yakuba; Drosophila melanogaster
Type:
Expression profiling by array
5 related Platforms
48 Samples
Download data
Series
Accession:
GSE2642
ID:
200002642
8.

Evolution of gene expression in the Drosophila melanogaster subgroup

(Submitter supplied) Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition-the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...
Organism:
Drosophila melanogaster; Drosophila simulans; Drosophila yakuba
Type:
Expression profiling by array
Platforms:
GPL227 GPL228
26 Samples
Download data
Series
Accession:
GSE327
ID:
200000327
9.

Drosophila simulans blue gut larvae vs. white prepupae

(Submitter supplied) Drosophila simulans blue gut larvae vs. white prepupae Keywords: repeat sample
Organism:
Drosophila simulans; Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL228
4 Samples
Download data
Series
Accession:
GSE134
ID:
200000134
10.

Drosophila melanogaster Samarkand blue gut larvae vs. white prepupae

(Submitter supplied) Drosophila melanogaster Samarkand blue gut larvae vs. white prepupae Keywords: repeat sample
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL228
6 Samples
Download data
Series
Accession:
GSE133
ID:
200000133
11.

Drosophila melanogaster OregonR blue gut larvae vs. white prepupae

(Submitter supplied) Drosophila melanogaster OregonR blue gut larvae vs. white prepupae Keywords: repeat sample
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL228
4 Samples
Download data
Series
Accession:
GSE132
ID:
200000132
12.

Drosophila melanogaster Netherlands2 blue gut larvae vs. white prepupae

(Submitter supplied) Drosophila melanogaster Netherlands2 blue gut larvae vs. white prepupae Keywords: repeat sample
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL228
4 Samples
Download data
Series
Accession:
GSE131
ID:
200000131
13.

Drosophila melanogaster CantonS blue gut larvae vs. white prepupae

(Submitter supplied) Drosophila melanogaster CantonS blue gut larvae vs. white prepupae Keywords: repeat sample
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL228
4 Samples
Download data
Series
Accession:
GSE130
ID:
200000130
14.

Drosophila yakuba white prepupae vs. blue gut larvae

(Submitter supplied) Drosophila yakuba white prepupae vs. blue gut larvae Keywords: repeat sample
Organism:
Drosophila melanogaster; Drosophila yakuba
Type:
Expression profiling by array
Platform:
GPL227
4 Samples
Download data
Series
Accession:
GSE129
ID:
200000129
15.

Expression profiling of five different xenobiotics using a C. elegans microarray

(Submitter supplied) Using a C. elegans whole genome DNA microarray in this study, the effects of five different xenobiotics on the gene expression of the nematode were investigated. The exposure time for the following five applied compounds beta-NF (5 mg/l), Fla (0.5 mg/l), atrazine (25 mg/l), clofibrate (10 mg/l) and DES (0.5 mg/l) was 48+/-5 h. The analysis of the data showed a clear induction of 203 genes belonging to different families like the cytochromes P450, UDP-glucoronosyltransferases (UDPGT), glutathione S-transferases (GST), carboxylesterases, collagenes, C-type lectins and others. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array
5 related Platforms
16 Samples
Download data
Series
Accession:
GSE4111
ID:
200004111
16.

Ethanol-response genes and their regulation

(Submitter supplied) The nematode shows responses to acute ethanol exposure that are similar to those observed in humans, mice, and Drosophila, namely hyperactivity followed by uncoordination and sedation. We used in this report the nematode Caenorhabditis elegans as a model system to identify and characterize the genes that are affected by ethanol exposure and to link those genes functionally into an ethanol-induced gene network. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array
Platforms:
GPL2653 GPL3097 GPL2646
7 Samples
Download data
Series
Accession:
GSE3727
ID:
200003727
17.

A404 Smooth Muscle Cell Differentiation

(Submitter supplied) In vitro time course experiment using the A404 clone of P19 mouse embryonal carcinoma cells to evaluate SMC differentiation in response to retinoic acid followed by phenotype-specific selection with puromycin. Four time points of 5-6 biological replicates each were performed. Keywords: time-course
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS799
Platform:
GPL1307
23 Samples
Download data
Series
Accession:
GSE1506
ID:
200001506
18.
Full record GDS799

Smooth muscle cell differentiation induced by retinoic acid: time course

Expression profiling of A404 cells at 48 and 96 hours following 1 umol/L all trans-retinoic acid (RA) treatment to induce differentiation into smooth muscle cells (SMCs). A set of cells treated with RA for 96 hours was subsequently treated with 0.5 ug/ml puromycin to enrich for SMCs.
Organism:
Mus musculus
Type:
Expression profiling by array, log ratio, 2 agent, 2 growth protocol, 3 time sets
Platform:
GPL1307
Series:
GSE1506
23 Samples
Download data
DataSet
Accession:
GDS799
ID:
799
19.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3643
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE10748
ID:
200010748
20.
Full record GDS3643

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 6 dose sets
Platform:
GPL1355
Series:
GSE10748
24 Samples
Download data: CEL
DataSet
Accession:
GDS3643
ID:
3643
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