Similar studies for GEO DataSets (Select 5914) - GEO DataSets

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Items: 19

Select item 59141.

YAP transcriptional regulator depletion effect on endothelial cells

Analysis of umbilical vein endothelial HUVEC cells depleted for the transcriptional regulator YAP. YAP binds to the SH3 domain of the transcriptional activator Yes. Results provide insight into the role of YAP in endothelial cell proliferation.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent, 2 protocol sets

Platform:: GPL6244
Series:: GSE61989
12 Samples

Download data: CEL

DataSet

Accession:: GDS5914

ID:: 5914

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000619892.

Expression data from HUVEC with YAP siRNA knockdown

(Submitter supplied) YAP knockdown in HUVEC elicits proliferation and cell cycle preogression defects. YAP deficient cells caused arrest in G1 and defects in S-phase entry. The microarray analysis was conducted to identify potential YAP targets that are involved in HUVEC cell cycle regulation

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5914
Platform:: GPL6244
12 Samples

Download data: CEL

Series

Accession:: GSE61989

ID:: 200061989

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000616283.

Mst1/2-Yap in lung epithelial progenitor cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL6246 GPL13112 GPL11154
14 Samples

Download data: CEL, TXT

Series

Accession:: GSE61628

ID:: 200061628

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000616274.

RNA-seq analysis of Mst1/2 deleted bronchiolar epithelial cells from adult mouse lungs

(Submitter supplied) Mst1 and Mst2 were conditionally deleted from non-ciliated bronchiolar epithelial cells in the mature lung. Bronchiolar epithelial cells from control and Mst1/2 deleted mice were isolated by cell sorting and used for RNA-seq analysis.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
2 Samples

Download data: TXT, XLS

Series

Accession:: GSE61627

ID:: 200061627

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000616265.

RNA-seq analysis of bronchosphere cultures of primary human bronchiolar epithelial cells

(Submitter supplied) Primary human bronchial epithelial cells were transduced with control or hYAP(S127A) lentivirus in sphere forming conditions. Bronchospheres were harvested on day 18-20 for RNAseq analysis

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
4 Samples

Download data: TXT, XLS

Series

Accession:: GSE61626

ID:: 200061626

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000615826.

Microarray of Mst1/2 deleted epithelial cells from E18.5 mouse lungs

(Submitter supplied) ShhCre;Mst1/2flx/flx (Mst1/2 D/D) mice were generated to conditionally delete Mst1 and Mst2 from epithelial progenitors during lung morphogenesis. Lungs from E18.5 control and Mst1/2 D/D mice were mechanically and enzymatically dissociated to generate single cell suspension. Epcam(+) cells were isolated using magnetic microbeads. Microarray analysis of mRNAs isolated from Epcam(+) epithelial cells from E18.5 control and Mst1/2 D/D mice was performed to identify transcriptional changes following deletion of the mammalian Hippo kinases (Mst1 and Mst2) from the embryonic lung.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
8 Samples

Download data: CEL

Series

Accession:: GSE61582

ID:: 200061582

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001081867.

miR-7977 transfer alter the transcriptome in bone marrow mesenchymal stem cells.

(Submitter supplied) Acute myeloid leukemia (AML) cells release abundant exosomal miR-7977 that transfer into bone marrow (BM) mesenchymal stromal cells (MSCs). We have shown that exosomal miR-7977 was highly released from AML cells and was transferred into BM MSCs. It has been well known that a microRNA has multiple targets. In fact, miRDB predicted 633 targets. Based on these findings, control and miR-7977mimic were transferred into BM MSCs. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16686
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE108186

ID:: 200108186

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001084228.

Analysis of gene expression levels between RacGAP1 silenced and control SMMC7721 cells

(Submitter supplied) To investigate the altered genes by RacGAP1 silencing

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE108422

ID:: 200108422

Select item 2000220119.

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

(Submitter supplied) We tested the hypothesis that increasing matrix stiffness on which normal human lung fibroblasts are grown promotes the expression of a fibrogenic cellular transcriptomic program. Keywords: Human lung fibroblast, matrix stiffness, PTGS2, COX-2, Prostaglandin E2

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
15 Samples

Download data: CEL

Series

Accession:: GSE22011

ID:: 200022011

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010758310.

Myc and YAP roles in the control of the cell cycle [MEF RNA-seq pharmacological treatment]

(Submitter supplied) Expression profiling by RNA-seq

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
16 Samples

Download data: XLSX

Series

Accession:: GSE107583

ID:: 200107583

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008386911.

Myc and YAP roles in the control of the cell cycle

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13112
107 Samples

Download data: BED, TXT

Series

Accession:: GSE83869

ID:: 200083869

PubMed Full text in PMC Similar studies

Select item 20008386812.

Myc and YAP roles in the control of the cell cycle [3T9 RNA-seq pharmacological treatment]

(Submitter supplied) RNAseq analysis of YAP and Myc induced in quiescent and confluent 3T9 fibroblasts treated with Y27632 and Verteporfin

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
12 Samples

Download data: XLSX

Series

Accession:: GSE83868

ID:: 200083868

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008386713.

Myc and YAP roles in the control of the cell cycle [3T9 RNA-seq]

(Submitter supplied) RNAseq analysis of YAP and Myc induced in quiescent and confluent 3T9 fibroblasts

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
12 Samples

Download data: TXT

Series

Accession:: GSE83867

ID:: 200083867

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008386614.

Myc and YAP roles in the control of the cell cycle [3T9 ChIP-seq]

(Submitter supplied) ChIPseq analysis of YAP and Myc induced in quiescent and confluent 3T9 fibroblasts

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13112
5 Samples

Download data: TXT

Series

Accession:: GSE83866

ID:: 200083866

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008386515.

Myc and YAP roles in the control of the cell cycle [Liver RNA-seq]

(Submitter supplied) RNAseq analysis was performed on liver of tet-YAP and tet-Myc transgenic mice induced for 2 days (R26-mice) or 4 weeks (laptTA-mice) or in liver tumor noduli.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
38 Samples

Download data: XLS

Series

Accession:: GSE83865

ID:: 200083865

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008386316.

Myc and YAP roles in the control of the cell cycle [Liver ChIP-seq]

(Submitter supplied) ChIPseq analysis was performed on liver of tet-YAP and tet-Myc transgenic mice induced for 2 days (R26-mice)

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13112
24 Samples

Download data: BED, TXT

Series

Accession:: GSE83863

ID:: 200083863

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006552417.

Next Generation Sequencing Identifies Hoxa1 and Hoxc13 as Downstream Targets of Yap in Mouse Epithelial Tissues

(Submitter supplied) The goals of this study are to identify in vivo downstream targets of Yap through NGS-derived tooth germ transcriptome profiling. The mRNA profiles of wild-type, Yap conditional knockout (CKO) and YAP transgenic (Tg) mouse tooth germs at embryonic day 14.5 were generated by deep sequencing using Illumina Hiseq2000. The sequence reads that passed quality filters were analyzed at the transcript isoform level via DNAnexus. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
4 Samples

Download data: TXT

Series

Accession:: GSE65524

ID:: 200065524

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20005306318.

Identification of TEAD4 target genes in colorectal cancer cells

(Submitter supplied) We have identified TEAD4 as a key prognosis factor in colorectal cancer. To elucidate the potentail mechanism and function of TEAD4 in colorectal caner, we generated two stable cell lines expressing different shRNA targeting TEAD4 in the mesenchymal-like LoVo cells and the differential genes were detected by microarray.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17077
3 Samples

Download data: TXT

Series

Accession:: GSE53063

ID:: 200053063

Select item 20009797219.

ChIP-seq analysis of MCF10A cells exressing active mutant YAP-5SA

(Submitter supplied) To understand the direct target genes YAP transcription co-activator invovled with in gonome-wide levels, next generation sequencing was conducted in Flag-YAP-5SA overexpressing MCF10A cells using Flag (sigma) antibody.