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Full record GDS4754

TYK2 and STAT1 silencing effect on JURKAT T-cell acute lymphoblastic leukemia cell line

Analysis of JURKAT cells transduced with TYK2 and STAT1 shRNAs. JAK tyrosine kinase TYK2 and downstream effector STAT1 promote survival of T-ALL cells. Results provide insight into the molecular mechanisms underlying TYK2-STAT1 pathway dependence in T-cell ALL.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 protocol sets
Platform:
GPL570
Series:
GSE44652
12 Samples
Download data: CEL

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