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Full record GDS4769

Radiation chimera model: Trp53-null mammary tumors arising from irradiated, TGFb1 heterozygote hosts

Analysis of Trp53-null tumors arising from Tgfb1+/- hosts cleared of mammary gland epithelia, irradiated, then transplanted with nonmalignant Trp53-null mammary tissue. TGF-β drives EMT and is highly induced by IR. Results provide insight into host biology contributions to radiation carcinogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 protocol sets
Platform:
GPL1261
Series:
GSE42742
24 Samples
Download data: CEL

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