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Full record GDS4893

Heart response to isocitrate dehydrogenase 2 mutations IDH2R140Q and IDH2R172K

Analysis of hearts from transgenics with conditionally-activated isocitrate dehydrogenase 2 mutant (IDH2) R140Q and R172K alleles. Mutant IDH2 causes cardiomyopathy and neurodegeneration. Results provide insight into molecular mechanisms underlying the cardiac defects associated with IDH2 mutations.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 genotype/variation sets
Platform:
GPL6246
Series:
GSE54838
12 Samples
Download data: CEL

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