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Full record GDS5676

Mutant isocitrate dehydrogenase 1 and 2 effect on hepatoblasts grown on collagen-coated plates

Analysis of hepatoblasts expressing mutant IDH1 (R132C) and mutant IDH2 (R172K) grown on collagen-coated plates. IDH genes are frequently mutated in intrahepatic cholangiocarcinoma (IHCC). Results provide insight into molecular pathways by which IDH mutations lead to tumor formation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 5 genotype/variation sets
Platform:
GPL8321
Series:
GSE57002
10 Samples
Download data: CEL

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